About the Authors

Edward R. Cachay

Affiliation School of Medicine, University of California San Diego, San Diego, California, United States of America

Amy Sitapati

Affiliation School of Medicine, University of California San Diego, San Diego, California, United States of America

Joseph Caperna

Affiliation School of Medicine, University of California San Diego, San Diego, California, United States of America

Kellie Freeborn

Affiliation School of Medicine, University of California San Diego, San Diego, California, United States of America

Joseph T. Lonergan

Affiliation School of Medicine, University of California San Diego, San Diego, California, United States of America

Edward Jocson

Affiliation School of Medicine, University of California San Diego, San Diego, California, United States of America

William C. Mathews

cmathews@ucsd.edu

Affiliation School of Medicine, University of California San Diego, San Diego, California, United States of America

for the Owen Clinic Study Group

Affiliation School of Medicine, University of California San Diego, San Diego, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ERC AS WCM. Performed the experiments: ERC AS JC WCM. Analyzed the data: ERC WCM. Contributed reagents/materials/analysis tools: ERC JC WCM. Wrote the paper: ERC AS JC WCM. Grant writing for funding the study: ERC AS. Patient accrual and data monitoring: ERC AS JC. Patient accrual: KF JTL EJ. Reviewed and edited manuscript: KF JTL EJ.