About the Authors
- Toshinori Hinoue
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Affiliations USC Epigenome Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America, Department of Surgery and Department of Biochemistry and Molecular Biology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
- Daniel J. Weisenberger
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Affiliation USC Epigenome Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
- Fei Pan
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Affiliation USC Epigenome Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
- Mihaela Campan
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Affiliation Department of Surgery and Department of Biochemistry and Molecular Biology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
- Myungjin Kim
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Affiliation Department of Surgery and Department of Biochemistry and Molecular Biology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
- Joanne Young
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Affiliations Familial Cancer Laboratory, Queensland Institute of Medical Research, Herston, Queensland, Australia, University of Queensland School of Medicine, Herston, Queensland, Australia
- Vicki L. Whitehall
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Affiliation Conjoint Gastroenterology Laboratory, Clinical Research Centre, Royal Brisbane and Women's Hospital Research Foundation, Herston, Queensland, Australia
- Barbara A. Leggett
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Affiliation Conjoint Gastroenterology Laboratory, Clinical Research Centre, Royal Brisbane and Women's Hospital Research Foundation, Herston, Queensland, Australia
- Peter W. Laird
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* E-mail: plaird@usc.edu
Affiliations USC Epigenome Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America, Department of Surgery and Department of Biochemistry and Molecular Biology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
Competing Interests
Peter Laird is a consultant for Epigenomics AG and for Celgene Corporation. The other authors disclosed no potential competing interest. This work was not supported by either Epigenomics AG or Celgene Corporation. These companies had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Author Contributions
Conceived and designed the experiments: TH DJW PWL. Performed the experiments: TH MK. Analyzed the data: TH. Contributed reagents/materials/analysis tools: JY VLW BL PWL. Wrote the paper: TH. Provided input on statistical analyses: FP. Provided experimental advice and discussion regarding data interpretation: MC.