About the Authors

Ge Zhang

Contributed equally to this work with: Ge Zhang, Xin-Luan Wang, Hui Sheng

Affiliation Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, China

Xin-Luan Wang

Contributed equally to this work with: Ge Zhang, Xin-Luan Wang, Hui Sheng

Affiliation Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, China

Hui Sheng

Contributed equally to this work with: Ge Zhang, Xin-Luan Wang, Hui Sheng

Affiliations Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, China, Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China

Xin-Hui Xie

Affiliation Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, China

Yi-Xin He

Affiliation Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, China

Xin-Sheng Yao

Affiliation Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guang Zhou, China

Zi-Rong Li

Affiliation Center for Osteonecrosis and Joint Preserving and Reconstruction, Department of Orthopaedic Surgery, Sino-Japan Friendship Hospital, Beijing, China

Kwong-Man Lee

Affiliation Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China

Wei He

Affiliation Department of Orthopaedics & Traumatology, The First Hospital Affiliated to Guang Zhou University of Traditional Chinese Medicine, Guang Zhou, China

Kwok-Sui Leung

Affiliation Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, China

Ling Qin

yaoxs@jnu.edu.cn

Affiliation Musculoskeletal Research Laboratory, Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, China

Competing Interests

β€œThe procedures employed for isolation of flavonoids from herbal Epimedium has been registered for patent application (International Application Number:PCT/CN2008/000165 issued by World Intellectual Property Organization).”

Author Contributions

Conceived and designed the experiments: GZ XLW HS. Performed the experiments: GZ XLW HS. Analyzed the data: GZ XLW HS. Contributed reagents/materials/analysis tools: GZ XLW HS XHX YXH XSY ZRL KML WH KSL LQ. Wrote the paper: GZ XLW HS.