About the Authors

Ilja M. Nolte

Affiliation Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

Chris Wallace

Affiliation Clinical Pharmacology and Barts and the London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom

Stephen J. Newhouse

Affiliation Clinical Pharmacology and Barts and the London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom

Daryl Waggott

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

Jingyuan Fu

Affiliations Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands, Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

Nicole Soranzo

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Department of Twin Research and Genetic Epidemiology Unit, St Thomas' Campus, King's College London, St Thomas' Hospital, London, United Kingdom

Rhian Gwilliam

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

Panos Deloukas

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom

Irina Savelieva

Affiliation Cardiological Sciences, Division of Cardiac and Vascular Sciences, St George's University of London, London, United Kingdom

Dongling Zheng

Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

Chrysoula Dalageorgou

Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

Martin Farrall

Affiliation Department of Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Nilesh J. Samani

Affiliation Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, United Kingdom

John Connell

Affiliation BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow, United Kindom

Morris Brown

Affiliation Clinical Pharmacology and the Cambridge Institute of Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

Anna Dominiczak

Affiliation BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow, United Kindom

Mark Lathrop

Affiliation Centre National de Genotypage, Evry, France

Eleftheria Zeggini

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Louise V. Wain

Affiliation Departments of Health Sciences & Genetics, University of Leicester, Leicester, United Kingdom

for the The Wellcome Trust Case Control Consortium

aFor the full author list see Appendix S1.

The DCCT/EDIC Research Group

bA complete list of investigators and members of the DCCT/EDIC Research Group appears in N Engl J Med 2005; 353(25):2643–53.

Christopher Newton-Cheh

Affiliations Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, NHLBI's Framingham Heart Study, Framingham, Massachusetts, United States of America

Mark Eijgelsheim

Affiliation Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

Kenneth Rice

Affiliation Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

Paul I. W. de Bakker

Affiliations Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School-Partners HealthCare Center for Genetics and Genomics, Boston, Massachusetts, United States of America

for the QTGEN consortium

cA complete list of investigators and members of the QTGEN consortium appears in Appendix S1.

Arne Pfeufer

Affiliations Institute of Human Genetics, Technical University Munich, Munich, Germany, Institute of Human Genetics, Helmholtz Center Munich, Munich, Germany

Serena Sanna

Affiliation Istituto di Neurogenetica e Neurofarmacologia, CNR, Monserrato, Cagliari, Italy

Dan E. Arking

Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

for the QTSCD consortium

dA complete list of investigators and members of the QTSCD consortium appears in Appendix S1.

Folkert W. Asselbergs

Affiliations Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands, Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

Tim D. Spector

Affiliation Department of Twin Research and Genetic Epidemiology Unit, St Thomas' Campus, King's College London, St Thomas' Hospital, London, United Kingdom

Nicholas D. Carter

Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

Steve Jeffery

Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

Martin Tobin

Affiliation Departments of Health Sciences & Genetics, University of Leicester, Leicester, United Kingdom

Mark Caulfield

Affiliation Clinical Pharmacology and Barts and the London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom

Harold Snieder

Affiliations Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands, Department of Twin Research and Genetic Epidemiology Unit, St Thomas' Campus, King's College London, St Thomas' Hospital, London, United Kingdom

Andrew D. Paterson

Affiliation Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Ontario, Canada

Patricia B. Munroe

Contributed equally to this work with: Patricia B. Munroe, Yalda Jamshidi

Affiliation Clinical Pharmacology and Barts and the London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom

Yalda Jamshidi

Contributed equally to this work with: Patricia B. Munroe, Yalda Jamshidi

y.jamshidi@sgul.ac.uk

Affiliation Division of Clinical Developmental Sciences, St George's University of London, London, United Kingdom

Competing Interests

Aravinda Chakravarti is a paid member of the Scientific Advisory Board of Affymetrix, a role that is managed by the Committee on Conflict of Interest of the Johns Hopkins University School of Medicine.

Author Contributions

Conceived and designed the experiments: CW MJC HS AP PM YJ. Analyzed the data: IMN CW SJN DW JF NS EZ LVW MDT HS AP PM YJ. Wrote the paper: IMN MDT MJC HS AP PM YJ. GWAS genotyping team: RG PD. Data collection and phenotyping: IS DZ CD MF NJS JC MB AD GML CNC FWA TDS NC SJ. In silico data: ME KR PdB AP SS DEA.