About the Authors

Valentina D. Mangano

vmangano@well.ox.ac.uk

Affiliations Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom, Department of Public Health Sciences, Section of Parasitology, University of Rome La Sapienza, Rome, Italy

Taane G. Clark

Affiliations Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Sarah Auburn

Contributed equally to this work with: Sarah Auburn, Susana Campino, Mahamadou Diakite, Andrew E. Fry

Affiliations Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Susana Campino

Contributed equally to this work with: Sarah Auburn, Susana Campino, Mahamadou Diakite, Andrew E. Fry

Affiliations Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Mahamadou Diakite

Contributed equally to this work with: Sarah Auburn, Susana Campino, Mahamadou Diakite, Andrew E. Fry

Affiliation Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Andrew E. Fry

Contributed equally to this work with: Sarah Auburn, Susana Campino, Mahamadou Diakite, Andrew E. Fry

Affiliation Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Angela Green

Affiliation Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Anna Richardson

Affiliation Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Muminatou Jallow

Affiliation Medical Research Council, Fajara, The Gambia

Fatou Sisay-Joof

Affiliation Medical Research Council, Fajara, The Gambia

Margaret Pinder

Affiliation Medical Research Council, Fajara, The Gambia

Michael J. Griffiths

Affiliation Kenya Medical Research Institute Centre for Geographical Medicine Research (Coast), Kilifi, Kenya

Charles Newton

Affiliation Kenya Medical Research Institute Centre for Geographical Medicine Research (Coast), Kilifi, Kenya

Norbert Peshu

Affiliation Kenya Medical Research Institute Centre for Geographical Medicine Research (Coast), Kilifi, Kenya

Thomas N. Williams

Affiliations Kenya Medical Research Institute Centre for Geographical Medicine Research (Coast), Kilifi, Kenya, Nuffield Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom

Kevin Marsh

Affiliations Kenya Medical Research Institute Centre for Geographical Medicine Research (Coast), Kilifi, Kenya, Nuffield Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom

Malcolm E. Molyneux

Affiliations The Malawi–Liverpool–Wellcome Trust Programme of Clinical Tropical Research, Blantyre Malaria Project, College of Medicine, Blantyre, Malawi, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

Terrie E. Taylor

Affiliations The Malawi–Liverpool–Wellcome Trust Programme of Clinical Tropical Research, Blantyre Malaria Project, College of Medicine, Blantyre, Malawi, Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United Kingdom

David Modiano

Affiliation Department of Public Health Sciences, Section of Parasitology, University of Rome La Sapienza, Rome, Italy

Dominic P. Kwiatkowski

Affiliations Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom, Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Kirk A. Rockett

Affiliation Childhood Infection Group, The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VDM DM DPK KR. Performed the experiments: VDM SA SC MD AEF AG AR. Analyzed the data: VDM TGC KR. Contributed reagents/materials/analysis tools: DPK KR. Wrote the paper: VDM TGC DM DPK KR. Conducted the clinical studies: MJ FSJ MP MG CRJCN NP TW KM MEM TET.