About the Authors

Guilian Xu

Affiliations Department of Neuroscience, McKnight Brain Institute, Santa Fe Health Alzheimer's Disease Research Center, University of Florida, Gainesville, Florida, United States of America, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Celeste Karch

Affiliations Department of Neuroscience, McKnight Brain Institute, Santa Fe Health Alzheimer's Disease Research Center, University of Florida, Gainesville, Florida, United States of America, Interdisciplinary Graduate Program, University of Florida, Gainesville, Florida, United States of America

Ning Li

Affiliation Interdisciplinary Graduate Program, University of Florida, Gainesville, Florida, United States of America

Nianwei Lin

Affiliation Interdisciplinary Graduate Program, University of Florida, Gainesville, Florida, United States of America

David Fromholt

Affiliations Department of Neuroscience, McKnight Brain Institute, Santa Fe Health Alzheimer's Disease Research Center, University of Florida, Gainesville, Florida, United States of America, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Victoria Gonzales

Affiliation Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

David R. Borchelt

borchelt@mbi.ufl.edu

Affiliations Department of Neuroscience, McKnight Brain Institute, Santa Fe Health Alzheimer's Disease Research Center, University of Florida, Gainesville, Florida, United States of America, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GX DRB. Performed the experiments: GX CK NL NL VG DF DRB. Analyzed the data: GX DRB. Wrote the paper: GX DRB.