About the Authors

Hongjie Yu

Contributed equally to this work with: Hongjie Yu, Zhancheng Gao, Zijian Feng, Yuelong Shu

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Zhancheng Gao

Contributed equally to this work with: Hongjie Yu, Zhancheng Gao, Zijian Feng, Yuelong Shu

gaozhancheng5446@163.com (ZG); yangwz@chinacdc.cn (WY)

Affiliation Department of Respiratory Medicine, Peking University People's Hospital, Beijing, China

Zijian Feng

Contributed equally to this work with: Hongjie Yu, Zhancheng Gao, Zijian Feng, Yuelong Shu

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Yuelong Shu

Contributed equally to this work with: Hongjie Yu, Zhancheng Gao, Zijian Feng, Yuelong Shu

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, China CDC, Beijing, China

Nijuan Xiang

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Lei Zhou

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Yang Huai

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Luzhao Feng

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Zhibin Peng

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Zhongjie Li

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Cuiling Xu

Affiliation State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, China CDC, Beijing, China

Junhua Li

Affiliation Hunan Provincial Center for Disease Control and Prevention, Changsha, China

Chengping Hu

Affiliation Xiang Ya Hospital of Central South University, Changsha, China

Qun Li

Affiliation Anhui Provincial Center for Disease Control and Prevention, Hefei, China

Xiaoling Xu

Affiliation Anhui Provincial Hospital, Hefei, China

Xuecheng Liu

Affiliation Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China

Zigui Liu

Affiliation Huaxi Hospital, Sichuan University, Chengdu, China

Longshan Xu

Affiliation Fujian Provincial Center for Disease Control and Prevention, Fuzhou, China

Yusheng Chen

Affiliation Fujian Provincial Hospital, Fuzhou, China

Huiming Luo

Affiliation Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China

Liping Wei

Affiliation Third Affiliated Hospital, Guangzhou Medical College, Guangzhou, China

Xianfeng Zhang

Affiliation Hubei Provincial Center for Disease Control and Prevention, Wuhan, China

Jianbao Xin

Affiliation Hankou Union Hospital, Hubei Province, Wuhan, China

Junqiao Guo

Affiliation Liaoning Provincial Center for Disease Control and Prevention, Shenyang, China

Qiuyue Wang

Affiliation First Affiliated Hospital, China Medical University, Shenyang, China

Zhengan Yuan

Affiliation Shanghai Center for Disease Control and Prevention, Shanghai, China

Longnv Zhou

Affiliation Ninth Affiliated Hospital, Shanghai Transportation University, Shanghai, China

Kunzhao Zhang

Affiliation Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, China

Wei Zhang

Affiliation First Affiliated Hospital, Nanchang University, Nanchang, China

Jinye Yang

Affiliation Guangxi Provincial Center for Disease Control and Prevention, Nanning, China

Xiaoning Zhong

Affiliation First Affiliated Hospital, Guangxi Medical University, Nanning, China

Shichang Xia

Affiliation Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China

Lanjuan Li

Affiliation First Affiliated Hospital, Zhejiang University, Hangzhou, China

Jinquan Cheng

Affiliation Shenzhen Center for Disease Control and Prevention, Shenzhen, China

Erdang Ma

Affiliation Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi, China

Pingping He

Affiliation Department of Epidemiology and Biostatistics School of Public Health, Health Science Center, Peking University, Beijing, China

Shui Shan Lee

Affiliation Centre for Emerging Infectious Diseases, Chinese University of Hong Kong, Hong Kong Special Administrative Region, China

Yu Wang

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Timothy M. Uyeki

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Weizhong Yang

gaozhancheng5446@163.com (ZG); yangwz@chinacdc.cn (WY)

Affiliation Office for Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Wrote the paper: HY TU. Designed the protocal of investigation, set up the field clinical investigation, contacted all investigators: HY ZG ZF YS WY. Responsible for the virus isolation, microneutralisation, hemagglutination inhibition assay, RT PCR, and real-time RT PCR testing, including the experimental design and analysis of data: YS CX. Participated in collection and management of data: NX LZ YH LF ZP ZL JL CH QL XX XL ZL LX YC HL LW XZ JX JG QW ZY LZ KZ WZ JY XZ SX LL JC EM PH SSL YW. Provided technical assistance for the clinical investigations and helped to review the data: TU.