About the Authors

Erhan Bilal

Affiliation BioMaPS Institute, Rutgers University, Piscataway, New Jersey, United States of America

Raul Rabadan

Affiliation Simons Center for Systems Biology, Institute for Advanced Study, Princeton, New Jersey, United States of America

Gabriela Alexe

Affiliation Computational Biology and Bioinformatics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Noriyuki Fuku

Affiliation Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan

Hitomi Ueno

Affiliation Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan

Yutaka Nishigaki

Affiliation Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan

Yasunori Fujita

Affiliation Department of Longevity and Aging Research, Gifu International Institute of Biotechnology, Kakamigahara, Gifu, Japan

Masafumi Ito

Affiliation Department of Longevity and Aging Research, Gifu International Institute of Biotechnology, Kakamigahara, Gifu, Japan

Yasumichi Arai

Affiliation Department of Geriatric Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

Nobuyoshi Hirose

Affiliation Department of Geriatric Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan

Andrei Ruckenstein

Affiliation Department of Physics, Boston University, Boston, Massachusetts, United States of America

Gyan Bhanot

Affiliations BioMaPS Institute, Rutgers University, Piscataway, New Jersey, United States of America, Simons Center for Systems Biology, Institute for Advanced Study, Princeton, New Jersey, United States of America, Department of Biomedical Engineering, Rutgers University, Piscataway, New Jersey, United States of America

Masashi Tanaka

mtanaka@tmig.or.jp

Affiliation Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MT GB. Performed the experiments: NF HU YN YF. Analyzed the data: MT RR GB GA EB AR. Contributed reagents/materials/analysis tools: MT MI YA NH. Wrote the paper: MT GB EB.