About the Authors

Daniel G. Wootton

Affiliations Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom, Malawi-Liverpool-Wellcome Trust Major Overseas Programme, College of Medicine, Blantyre, Malawi

Hyginus Opara

Affiliation MRC Laboratories, Banjul, Fajara, The Gambia

Giancarlo A. Biagini

Affiliation Liverpool School of Tropical Medicine, Liverpool, United Kingdom

Maxwell K. Kanjala

Affiliation Malawi-Liverpool-Wellcome Trust Major Overseas Programme, College of Medicine, Blantyre, Malawi

Stephan Duparc

Affiliation GlaxoSmithKline, Greenford, Middlesex, United Kingdom

Paula L. Kirby

Affiliation GlaxoSmithKline, Greenford, Middlesex, United Kingdom

Mary Woessner

Affiliation GlaxoSmithKline, Greenford, Middlesex, United Kingdom

Colin Neate

Affiliation GlaxoSmithKline, Greenford, Middlesex, United Kingdom

Maggie Nyirenda

Affiliation Department of Paediatrics, College of Medicine, Blantyre, Malawi

Hannah Blencowe

Affiliation Department of Paediatrics, College of Medicine, Blantyre, Malawi

Queen Dube-Mbeye

Affiliation Department of Paediatrics, College of Medicine, Blantyre, Malawi

Thomas Kanyok

Affiliation Global Health-Infectious Diseases, Bill and Melinda Gates Foundation, Seattle, Washington, United States of America (formerly at the WHO-UNDP-World Bank Special Programme for Research and Training in Tropical Medicine (WHO-TDR), Geneva, Switzerland)

Stephen Ward

Affiliation Liverpool School of Tropical Medicine, Liverpool, United Kingdom

Malcolm Molyneux

Affiliations Malawi-Liverpool-Wellcome Trust Major Overseas Programme, College of Medicine, Blantyre, Malawi, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

Sam Dunyo

Affiliation MRC Laboratories, Banjul, Fajara, The Gambia

Peter A. Winstanley

To whom correspondence should be addressed. E-mail: p.a.winstanley@liverpool.ac.uk

Affiliation Department of Pharmacology & Therapeutics, University of Liverpool, Liverpool, United Kingdom

Competing Interests

Paula Kirby and Mary Woessner are current employees of GlaxoSmithKline, and Stephan Duparc and Colin Neate are former employees of GlaxoSmithKline.

Author Contributions

Conceived and designed the experiments: MM SW PW GB SD PK MW CN TK. Performed the experiments: SD MK DW HO GB MN HB QD. Analyzed the data: MW CN. Wrote the paper: SD MM MK SW PW DW HO GB SD PK MW CN MN HB QD TK. Other: Developed the parasite viability assay protocol: GB SW. Managed the clinical trial: SD PK.