About the Authors

Nelson K. F. Chen

Affiliation Division of Medical Sciences, National Cancer Centre, Singapore, Republic of Singapore

Jen San Wong

Affiliations Division of Medical Sciences, National Cancer Centre, Singapore, Republic of Singapore, Department of General Surgery, Singapore General Hospital, Singapore, Republic of Singapore

Irene H. C. Kee

Affiliation Department of Experimental Surgery, Singapore General Hospital, Singapore, Republic of Singapore

Siang Hui Lai

Affiliation Centre for Forensic Medicine, Health Sciences Authority, Singapore, Republic of Singapore

Choon Hua Thng

Affiliation Department of Oncologic Imaging, National Cancer Centre, Singapore, Republic of Singapore

Wai Har Ng

Affiliation Division of Medical Sciences, National Cancer Centre, Singapore, Republic of Singapore

Robert T. H. Ng

Affiliation Department of Experimental Surgery, Singapore General Hospital, Singapore, Republic of Singapore

Soo Yong Tan

Affiliation Department of Pathology, Singapore General Hospital, Singapore, Republic of Singapore

Shu Yen Lee

Affiliation Singapore National Eye Centre, Singapore, Republic of Singapore

Mark E. H. Tan

Affiliation Division of Medical Sciences, National Cancer Centre, Singapore, Republic of Singapore

Jaichandran Sivalingam

Affiliation Division of Medical Sciences, National Cancer Centre, Singapore, Republic of Singapore

Pierce K. H. Chow

To whom correspondence should be addressed. E-mail: gsupc@sgh.com.sg (PC); dmskol@nccs.com.sg (OK)

Affiliations Department of General Surgery, Singapore General Hospital, Singapore, Republic of Singapore, Department of Experimental Surgery, Singapore General Hospital, Singapore, Republic of Singapore

Oi Lian Kon

To whom correspondence should be addressed. E-mail: gsupc@sgh.com.sg (PC); dmskol@nccs.com.sg (OK)

Affiliation Division of Medical Sciences, National Cancer Centre, Singapore, Republic of Singapore

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: OK NC. Performed the experiments: NC JW IK RN PC SHL WN MT JS CT SYL. Analyzed the data: OK NC SHL SYL ST. Contributed reagents/materials/analysis tools: OK PC. Wrote the paper: OK NC. Other: Provided training in surgical procedures, and performed liver resections and hepatocyte implantations: PC. Assisted in hepatocyte isolation and electroporation: JS MT. Performed all ocular examinations and analyses: SYL. Evaluated histological and electron microscopy sections: ST. Provided training: RN. Assisted in daily animal husbandary, clinical monitoring and all testing procedures on animals: RN NC. Performed ultrasonically guided percutaneous hepatocyte implantations: CT. Conducted all autopsies and evaluated histological samples: SHL. Performed daily animal husbandary, clinical monitoring and all testing procedures on animals: IK. Assisted in liver resections, hepatocyte isolation and implantations: IK. Performed liver resections and hepatocyte implantations, daily animal husbandary, clinical monitoring and all testing procedures on animals: JW. Asssisted in autopsies: IK JW WN NC. Performed hepatocyte isolation and electroporation, and all bench experiments: NC. Assisted in hepatocyte electroporation and bench experiments: WN.