About the Authors

Caitlin M. Conboy

Contributed equally to this work with: Caitlin M. Conboy, Christiana Spyrou

Affiliation Cancer Research UK-Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom

Christiana Spyrou

Contributed equally to this work with: Caitlin M. Conboy, Christiana Spyrou

Affiliations Cancer Research UK-Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom, Statistical Laboratory, Department of Pure Mathematics and Mathematical Statistics, University of Cambridge, Cambridge, United Kingdom

Natalie P. Thorne

Affiliations Cancer Research UK-Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom, Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge, United Kingdom

Elizabeth J. Wade

Affiliation Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, Connecticut, United States of America

Nuno L. Barbosa-Morais

Affiliation Cancer Research UK-Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom

Michael D. Wilson

Affiliation Cancer Research UK-Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom

Arindam Bhattacharjee

Affiliation Agilent Technologies, Andover, Massachusetts, United States of America

Richard A. Young

Affiliations Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Simon Tavaré

Affiliations Cancer Research UK-Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom, Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge, United Kingdom

Jacqueline A. Lees

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Duncan T. Odom

To whom correspondence should be addressed. E-mail: duncan.odom@cancer.org.uk

Affiliation Cancer Research UK-Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DO. Performed the experiments: DO CC EW MW. Analyzed the data: NT DO CC NB CS. Contributed reagents/materials/analysis tools: RY JL AB. Wrote the paper: RY JL NT DO ST CC CS MW.