About the Authors

Andre Franke

Affiliation Institute for Clinical Molecular Biology, Christian-Albrechts University Kiel, Kiel, Germany

Jochen Hampe

Affiliation First Department of Medicine, University Hospital Schleswig-Holstein, Kiel, Germany

Philip Rosenstiel

Affiliation Institute for Clinical Molecular Biology, Christian-Albrechts University Kiel, Kiel, Germany

Christian Becker

Affiliations Cologne Center for Genomics, University of Cologne, Köln, Germany, RZPD German Resource Center for Genome Research, Berlin, Germany

Florian Wagner

Affiliation RZPD German Resource Center for Genome Research, Berlin, Germany

Robert Häsler

Affiliation Institute for Clinical Molecular Biology, Christian-Albrechts University Kiel, Kiel, Germany

Randall D. Little

Affiliation Genizon BioSciences5, Québec, Canada

Klaus Huse

Affiliation Genome Analysis Group, Leibniz Institute for Age Research, Jena, Germany

Andreas Ruether

Affiliation PopGen Biobank, Christian-Albrechts University Kiel, Kiel, Germany

Tobias Balschun

Affiliation Institute for Clinical Molecular Biology, Christian-Albrechts University Kiel, Kiel, Germany

Michael Wittig

Affiliation PopGen Biobank, Christian-Albrechts University Kiel, Kiel, Germany

Abdou ElSharawy

Affiliation Institute for Clinical Molecular Biology, Christian-Albrechts University Kiel, Kiel, Germany

Gabriele Mayr

Affiliation Max-Planck Institute for Informatics, Saarbrücken, Germany

Mario Albrecht

Affiliation Max-Planck Institute for Informatics, Saarbrücken, Germany

Natalie J. Prescott

Affiliation Department of Medical and Molecular Genetics, King's College London School of Medicine, London, United Kingdom

Clive M. Onnie

Affiliation Department of Medical and Molecular Genetics, King's College London School of Medicine, London, United Kingdom

Hélène Fournier

Affiliation Genizon BioSciences5, Québec, Canada

Tim Keith

Affiliation Genizon BioSciences5, Québec, Canada

Uwe Radelof

Affiliation RZPD German Resource Center for Genome Research, Berlin, Germany

Matthias Platzer

Affiliation Genome Analysis Group, Leibniz Institute for Age Research, Jena, Germany

Christopher G. Mathew

Affiliation Department of Medical and Molecular Genetics, King's College London School of Medicine, London, United Kingdom

Monika Stoll

Affiliation Leibniz-Institute for Arteriosclerosis Research, University Münster, Münster, Germany

Michael Krawczak

Affiliations PopGen Biobank, Christian-Albrechts University Kiel, Kiel, Germany, Institute of Medical Statistics and Informatics, Christian-Albrechts University Kiel, Kiel, Germany

Peter Nürnberg

Affiliations Cologne Center for Genomics, University of Cologne, Köln, Germany, Center for Molecular Medicine Cologne, University of Cologne, Köln, Germany

Stefan Schreiber

To whom correspondence should be addressed. E-mail: s.schreiber@mucosa.de

Affiliations Institute for Clinical Molecular Biology, Christian-Albrechts University Kiel, Kiel, Germany, First Department of Medicine, University Hospital Schleswig-Holstein, Kiel, Germany, PopGen Biobank, Christian-Albrechts University Kiel, Kiel, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SS JH MA MP MK AF TK CM. Performed the experiments: PR KH AR CB AF AR TB MW GM RL HF CO FW CM NP UR AE RH. Analyzed the data: KH MS MK CB AF RL CO NP. Contributed reagents/materials/analysis tools: SS PN TK. Wrote the paper: AF.