About the Authors

Todd A. Sangster

Affiliations Committee on Genetics, University of Chicago, Chicago, Illinois, United States of America, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Adam Bahrami

Affiliation Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America

Amity Wilczek

Current address: Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island, United States of America,

Affiliation Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America

Etsuko Watanabe

Affiliation FAS Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America

Kurt Schellenberg

Affiliation FAS Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America

Catherine McLellan

Current address: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America,

Affiliation FAS Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America

Alicia Kelley

Current address: Plants, Soils, and Biometeorology Department, Utah State University, Logan, Utah, United States of America,

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Sek Won Kong

Affiliation Informatics Program, Children's Hospital Boston, Boston, Massachusetts, United States of America

Christine Queitsch

To whom correspondence should be addressed. E-mail: queitsch@u.washington.edu

Current address: Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America

Affiliation FAS Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America

Susan Lindquist

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CQ AB TS AW EW. Performed the experiments: CQ AB TS AW EW KS CM AK. Analyzed the data: CQ SK AB TS AW EW CM. Wrote the paper: CQ SL TS.