About the Authors

Michael A. Pickart

Current address: Department of Biology, University of Wisconsin – Stout, Menomonie, Wisconsin, United States of America

Affiliation Department of Oral Sciences and Minnesota Craniofacial Research Training Program MinnCResT, University of Minnesota, Minneapolis, Minnesota, United States of America

Eric W. Klee

Current address: Department of Laboratory Medicine and Pathology at the Mayo Clinic, Rochester, Minnesota, United States of America

Affiliation Laboratory Medicine and Pathology and Computer Science and Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America

Aubrey L. Nielsen

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, Minnesota, United States of America

Sridhar Sivasubbu

Current address: Institute of Genomics and Integrative Biology, Delhi, India

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, Minnesota, United States of America

Eric M. Mendenhall

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Medicine, Division of Hematology, Oncology, and Transplantation, and Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota, United States of America

Brent R. Bill

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Pediatrics, Genetics and Metabolism and Department of Ophthalmology, University of Minnesota, Minneapolis, Minnesota, United States of America

Eleanor Chen

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, Minnesota, United States of America

Craig E. Eckfeldt

Affiliation Department of Medicine, Division of Hematology, Oncology, and Transplantation, and Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota, United States of America

Michelle Knowlton

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, Minnesota, United States of America

Mara E. Robu

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Oral Sciences and Minnesota Craniofacial Research Training Program MinnCResT, University of Minnesota, Minneapolis, Minnesota, United States of America

Jon D. Larson

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, Minnesota, United States of America

Yun Deng

Affiliation Carnegie Institute of Washington, Baltimore, Maryland, United States of America

Lisa A. Schimmenti

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Pediatrics, Genetics and Metabolism and Department of Ophthalmology, University of Minnesota, Minneapolis, Minnesota, United States of America

Lynda B.M. Ellis

Affiliation Laboratory Medicine and Pathology and Computer Science and Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America

Catherine M. Verfaillie

Affiliation Department of Medicine, Division of Hematology, Oncology, and Transplantation, and Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota, United States of America

Matthias Hammerschmidt

Affiliation Max Planck Institute Immunbiologie, Freiburg, Germany

Steven A. Farber

Affiliation Carnegie Institute of Washington, Baltimore, Maryland, United States of America

Stephen C. Ekker

To whom correspondence should be addressed. E-mail: ekker001@umn.edu

Affiliations Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, United States of America, Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, Minnesota, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CE SE CV EM MH SS MR JL SF MP EK AN BB EC MK YD LS LE. Performed the experiments: CE EM MH SS MR JL SF MP EK AN BB EC MK YD. Analyzed the data: CE SE CV EM MH SS MR JL SF MP EK AN BB EC MK YD LS LE. Contributed reagents/materials/analysis tools: CE SE CV EM MH SS MR JL SF MP EK BB EC MK YD LE. Wrote the paper: SE SF MP EK.