About the Authors

Jennifer A. MacDiarmid

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Veronika Langova

Affiliation Small Animal Specialist Hospital, Sydney, New South Wales, Australia

Dale Bailey

Affiliation Department of Nuclear Medicine, Royal North Shore Hospital, Sydney, New South Wales, Australia

Scott T. Pattison

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Stacey L. Pattison

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Neil Christensen

Affiliation Small Animal Specialist Hospital, Sydney, New South Wales, Australia

Luke R. Armstrong

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Vatsala N. Brahmbhatt

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Katarzyna Smolarczyk

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Matthew T. Harrison

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Marylia Costa

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Nancy B. Mugridge

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Ilya Sedliarou

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Nicholas A. Grimes

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Debra L. Kiss

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Bruce Stillman

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Christine L. Hann

Affiliation Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Gary L. Gallia

Affiliations Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Robert M. Graham

Affiliations Victor Chang Cardiac Research Institute, Sydney, New South Wales, Australia, University of New South Wales, Sydney, New South Wales, Australia

Himanshu Brahmbhatt

hbrahmbhatt@engeneic.com

Affiliation Cancer Therapeutics, EnGeneIC Pty Ltd, Sydney, New South Wales, Australia

Competing Interests

EnGeneIC Pty Ltd funded the salaries for authors JAM, STP, SLP, LRA, VNB, KS, MTH, MC, NBM, IS, NAG, DLK, HB. Authors JAM, HB, NBM, STP, SLP, RMG, BS are shareholders in EnGeneIC Pty Ltd. All other authors declare that no competing interests exist. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HB JAM. Performed the experiments: JAM VL DB STP SLP NC LRA VNB KS MTH NBM IS HB. Analyzed the data: JAM VL DB STP SLP NC MTH MC NBM IS NAG DLK BS CLH GLG RMG HB. Contributed reagents/materials/analysis tools: VL STP SLP NC LRA VNB KS MTH NBM IS. Wrote the paper: JAM VL DB HB.