Genkwadaphnin Induces IFN-γ via PKD1/NF-κB/STAT1 Dependent Pathway in NK-92 Cells

Ho-Bum Kang; Kyung-Seop Ahn; Sei-Ryang Oh; Jae Wha Kim

doi:10.1371/journal.pone.0115146

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Open Access

Peer-reviewed

Research Article

Genkwadaphnin Induces IFN-γ via PKD1/NF-κB/STAT1 Dependent Pathway in NK-92 Cells

Ho-Bum Kang,

Affiliation Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea
⨯
Kyung-Seop Ahn,

Affiliation Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, 685-1 Yangchung-ri, Ochang-eup, Cheongwon-gun, Chungbuk, Republic of Korea
⨯
Sei-Ryang Oh,

Affiliation Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, 685-1 Yangchung-ri, Ochang-eup, Cheongwon-gun, Chungbuk, Republic of Korea
⨯
Jae Wha Kim

* E-mail: wjkim@kribb.re.kr

Affiliation Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea
⨯

Genkwadaphnin Induces IFN-γ via PKD1/NF-κB/STAT1 Dependent Pathway in NK-92 Cells

Ho-Bum Kang,
Kyung-Seop Ahn,
Sei-Ryang Oh,
Jae Wha Kim

Published: December 17, 2014
https://doi.org/10.1371/journal.pone.0115146

About the Authors

Ho-Bum Kang

Affiliation Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea

Kyung-Seop Ahn

Affiliation Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, 685-1 Yangchung-ri, Ochang-eup, Cheongwon-gun, Chungbuk, Republic of Korea

Sei-Ryang Oh

Affiliation Immune Modulator Research Center, Korea Research Institute of Bioscience and Biotechnology, 685-1 Yangchung-ri, Ochang-eup, Cheongwon-gun, Chungbuk, Republic of Korea

Jae Wha Kim

* E-mail: wjkim@kribb.re.kr

Affiliation Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HBK JWK. Performed the experiments: HBK. Analyzed the data: HBK KSA SRO JWK. Contributed reagents/materials/analysis tools: SRO KSA. Wrote the paper: HBK JWK.

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NK cells
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Immune response
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