About the Authors

Madhuri Sridharamurthy

Affiliations Laboratories of Structural Sciences/Structural Biology and Biochemistry, Van Andel Research Institute, N.E., Grand Rapids, Michigan, United States of America, Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore

Amanda Kovach

Affiliation Laboratories of Structural Sciences/Structural Biology and Biochemistry, Van Andel Research Institute, N.E., Grand Rapids, Michigan, United States of America

Yang Zhao

Affiliation Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, Indiana 47906, United States of America

Jian-Kang Zhu

Affiliation Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, Indiana 47906, United States of America

H. Eric Xu

Affiliations Laboratories of Structural Sciences/Structural Biology and Biochemistry, Van Andel Research Institute, N.E., Grand Rapids, Michigan, United States of America, State Key Laboratory of Drug Research, VARI-SIMM Center, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China

Kunchithapadam Swaminathan

dbsks@nus.edu.sg (KS); karsten.melcher@vai.org (KM)

Affiliation Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore

Karsten Melcher

dbsks@nus.edu.sg (KS); karsten.melcher@vai.org (KM)

Affiliation Laboratories of Structural Sciences/Structural Biology and Biochemistry, Van Andel Research Institute, N.E., Grand Rapids, Michigan, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JKZ HEX KS KM. Performed the experiments: MS AK YZ KM. Analyzed the data: JKZ HEX KS KM. Wrote the paper: MS KM AK YZ JKZ HEX KS.