About the Authors
- Federico Ambrogi
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Affiliation Unit of Medical Statistics, Biometry and Bioinformatics “Giulio A. Maccacaro”, Department of Clinical Sciences and Community Health, University of Milan, Milano, Italy
- Marco Fornili
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Affiliation Unit of Medical Statistics, Biometry and Bioinformatics “Giulio A. Maccacaro”, Department of Clinical Sciences and Community Health, University of Milan, Milano, Italy
- Patrizia Boracchi
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Affiliation Unit of Medical Statistics, Biometry and Bioinformatics “Giulio A. Maccacaro”, Department of Clinical Sciences and Community Health, University of Milan, Milano, Italy
- Marco Trerotola
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Affiliation Unit of Cancer Pathology, Department of Biomedical Sciences and CeSI, Fondazione ‘G. D'Annunzio’, University of Chieti, Chieti, Italy
- Valeria Relli
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Affiliation Unit of Cancer Pathology, Department of Biomedical Sciences and CeSI, Fondazione ‘G. D'Annunzio’, University of Chieti, Chieti, Italy
- Pasquale Simeone
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Affiliation Unit of Cancer Pathology, Department of Biomedical Sciences and CeSI, Fondazione ‘G. D'Annunzio’, University of Chieti, Chieti, Italy
- Rossana La Sorda
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Affiliations Unit of Cancer Pathology, Department of Biomedical Sciences and CeSI, Fondazione ‘G. D'Annunzio’, University of Chieti, Chieti, Italy, MediaPharma s.r.l., CeSI, University ‘G. D'Annunzio’, Chieti, Italy
- Rossano Lattanzio
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Affiliations Unit of Cancer Pathology, Department of Biomedical Sciences and CeSI, Fondazione ‘G. D'Annunzio’, University of Chieti, Chieti, Italy, MediaPharma s.r.l., CeSI, University ‘G. D'Annunzio’, Chieti, Italy
- Patrizia Querzoli
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Affiliation Section of Surgical Pathology, Department of Experimental and Diagnostic Medicine, University of Ferrara, Ferrara, Italy
- Massimo Pedriali
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Affiliation Section of Surgical Pathology, Department of Experimental and Diagnostic Medicine, University of Ferrara, Ferrara, Italy
- Mauro Piantelli
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Affiliations Unit of Cancer Pathology, Department of Biomedical Sciences and CeSI, Fondazione ‘G. D'Annunzio’, University of Chieti, Chieti, Italy, MediaPharma s.r.l., CeSI, University ‘G. D'Annunzio’, Chieti, Italy
- Elia Biganzoli
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Contributed equally to this work with: Elia Biganzoli, Saverio Alberti
Affiliations Unit of Medical Statistics, Biometry and Bioinformatics “Giulio A. Maccacaro”, Department of Clinical Sciences and Community Health, University of Milan, Milano, Italy, Fondazione IRCCS, Istituto Nazionale Tumori, Milano, Italy
- Saverio Alberti
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Contributed equally to this work with: Elia Biganzoli, Saverio Alberti
* E-mail: s.alberti@unich.it
Affiliations Unit of Cancer Pathology, Department of Biomedical Sciences and CeSI, Fondazione ‘G. D'Annunzio’, University of Chieti, Chieti, Italy, Department of Neurosciences, Imaging and Clinical Sciences – Physiology and Physiopathology, University of Chieti, Chieti, Italy, Oncoxx Biotech s.r.l., Chieti, Italy
Competing Interests
This study was partly funded by Oncoxx Biotech, and Dr. Saverio Alberti is President of this company. This affiliation does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. A patent related to this work is “Anti-Trop-2 monoclonal antibodies and uses thereof in the treatment and diagnosis of tumors” – PCT/IT2009/000035.
Author Contributions
Conceived and designed the experiments: SA. Performed the experiments: VR PS MT RLS RL. Analyzed the data: PQ RL M. Pedriali FA MF PB EB M. Piantelli. Wrote the paper: FA EB SA. Managed the revision of the manuscript: MT.