About the Authors

Sue Jordan

s.e.jordan@swansea.ac.uk

Affiliation Department of Nursing, The College of Human and Health Sciences, Swansea University, Singleton Park, Swansea, Wales, United Kingdom

Alan Watkins

Affiliation The College of Medicine, Swansea University, Singleton Park, Swansea, Wales, UK Wales, United Kingdom

Mel Storey

Affiliation The College of Medicine, Swansea University, Singleton Park, Swansea, Wales, UK Wales, United Kingdom

Steven J. Allen

Affiliation The College of Medicine, Swansea University, Singleton Park, Swansea, Wales, UK Wales, United Kingdom

Caroline J. Brooks

Affiliation The College of Medicine, Swansea University, Singleton Park, Swansea, Wales, UK Wales, United Kingdom

Iveta Garaiova

Affiliation Obsidian Research Limited, Baglan Industrial Park, Port Talbot, West Glamorgan, Wales, United Kingdom

Martin L. Heaven

Affiliation The College of Medicine, Swansea University, Singleton Park, Swansea, Wales, UK Wales, United Kingdom

Ruth Jones

Affiliation The College of Medicine, Swansea University, Singleton Park, Swansea, Wales, UK Wales, United Kingdom

Sue F. Plummer

Affiliation Obsidian Research Limited, Baglan Industrial Park, Port Talbot, West Glamorgan, Wales, United Kingdom

Ian T. Russell

Affiliation The College of Medicine, Swansea University, Singleton Park, Swansea, Wales, UK Wales, United Kingdom

Catherine A. Thornton

Affiliation The College of Medicine, Swansea University, Singleton Park, Swansea, Wales, UK Wales, United Kingdom

Gareth Morgan

Affiliation The College of Medicine, Swansea University, Singleton Park, Swansea, Wales, UK Wales, United Kingdom

Competing Interests

S. Jordan, S. J. Allen, C. A. Thornton, A. Watkins, R. Jones, I. Russell, C. J. Brooks, M. L. Heaven, and G. Morgan declare no conflicts of interest. M. Storey received financial support from Cultech Ltd. I. Garaiova is a Senior Research Manager and S. F. Plummer is the Managing Director, Obsidian Research Ltd. The affiliations of two authors and the commercial funding, along with any other relevant declarations relating to employment, products in development does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed in the online guide for authors. The product in the trial was not commercially available at the time of the trial.

Author Contributions

Conceived and designed the experiments: SJ SA SP CT GM. Performed the experiments: SJ MS SA CB IG MH RJ GM. Analyzed the data: SJ AW IR. Contributed reagents/materials/analysis tools: CB MH IG SP. Wrote the paper: SJ AW MS SP IR GM. Commented on drafts and approved the final manuscript: SJ AW MS SA CB IG MH RJ SP IR CT GM.