About the Authors

Masato Yano

Contributed equally to this work with: Masato Yano, Tadashi Yamamoto

myano@gpo.kumamoto-u.ac.jp (MY); oike@gpo.kumamoto-u.ac.jp (YO)

Affiliation Department of Molecular Genetics, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Tadashi Yamamoto

Contributed equally to this work with: Masato Yano, Tadashi Yamamoto

Affiliations Department of Molecular Genetics, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, Department of Cardiovascular Medicine, Saga University, Saga, Japan

Naotaka Nishimura

Affiliation Department of Molecular Genetics, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Tomomi Gotoh

Affiliation Department of Molecular Genetics, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Ken Watanabe

Affiliation Department of Bone & Joint Disease, National Center for Geriatrics and Gerontology, Japan

Kazutaka Ikeda

Current address: Institute for Advanced Biosciences, Keio University, Yamagata, Japan

Affiliation Department of Metabolome, Graduate School of Medicine, University of Tokyo, Tokyo, Japan and CREST, JST, Tokyo, Japan

Yohei Garan

Affiliation Department of Molecular Genetics, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Ryo Taguchi

Current address: Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Aichi, Japan

Affiliation Department of Metabolome, Graduate School of Medicine, University of Tokyo, Tokyo, Japan and CREST, JST, Tokyo, Japan

Koichi Node

Affiliation Department of Cardiovascular Medicine, Saga University, Saga, Japan

Toshiro Okazaki

Current address: Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan

Affiliation Division of Clinical Laboratory Medicine and Hematology/Oncology, Faculty of Medicine, Tottori University, Tottori, Japan

Yuichi Oike

myano@gpo.kumamoto-u.ac.jp (MY); oike@gpo.kumamoto-u.ac.jp (YO)

Affiliation Department of Molecular Genetics, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MY TY KW. Performed the experiments: MY TY NN KW KI YG. Analyzed the data: MY TY NN TG KW KI RT KN TO YO. Contributed reagents/materials/analysis tools: MY TG YO. Wrote the paper: MY.