Free-ranging domestic dogs Canis familiaris from a rural Chadian village, collared with GPS and proximity loggers. Free-ranging domestic dogs are susceptible to a number of zoonotic infections. High resolution contact networks derived from the proximity loggers demonstrated heterogeneity in contact rates. Simulations on the contact networks for an infection comparable to rabies found epidemic outcomes were determined by the seeded individual's network position, which was also correlated with ranging behaviour. Wilson-Aggarwal, et al. (2019)
Image Credit: Jared Wilson-Aggarwal
Viewpoints
Globalists versus nationalists: Bridging the divide through blue marble health
PLOS Neglected Tropical Diseases: published July 11, 2019 | https://doi.org/10.1371/journal.pntd.0007156
Hepatitis E should be considered a neglected tropical disease
PLOS Neglected Tropical Diseases: published July 25, 2019 | https://doi.org/10.1371/journal.pntd.0007453
Galactose as novel target against Acanthamoeba cysts
PLOS Neglected Tropical Diseases: published July 26, 2019 | https://doi.org/10.1371/journal.pntd.0007385
Policy Platform
From river blindness to river epilepsy: Implications for onchocerciasis elimination programmes
PLOS Neglected Tropical Diseases: published July 18, 2019 | https://doi.org/10.1371/journal.pntd.0007407
Review
Leishmania tarentolae: Taxonomic classification and its application as a promising biotechnological expression host
PLOS Neglected Tropical Diseases: published July 25, 2019 | https://doi.org/10.1371/journal.pntd.0007424
Research Articles
Economic performance and cost-effectiveness of using a DEC-salt social enterprise for eliminating the major neglected tropical disease, lymphatic filariasis
PLOS Neglected Tropical Diseases: published July 1, 2019 | https://doi.org/10.1371/journal.pntd.0007094
Model-based assessment of public health impact and cost-effectiveness of dengue vaccination following screening for prior exposure
PLOS Neglected Tropical Diseases: published July 1, 2019 | https://doi.org/10.1371/journal.pntd.0007482
Early identification of acute kidney injury in Russell’s viper (Daboia russelii) envenoming using renal biomarkers
PLOS Neglected Tropical Diseases: published July 1, 2019 | https://doi.org/10.1371/journal.pntd.0007486
Evaluation of methods for detection of asymptomatic individuals infected with Leishmania infantum in the state of Piauí, Brazil
PLOS Neglected Tropical Diseases: published July 1, 2019 | https://doi.org/10.1371/journal.pntd.0007493
Intestinal parasitic infection alters bone marrow derived dendritic cell inflammatory cytokine production in response to bacterial endotoxin in a diet-dependent manner
PLOS Neglected Tropical Diseases: published July 1, 2019 | https://doi.org/10.1371/journal.pntd.0007515
Leishmania major degrades murine CXCL1 – An immune evasion strategy
PLOS Neglected Tropical Diseases: published July 1, 2019 | https://doi.org/10.1371/journal.pntd.0007533
Development and validation of an Onchocerca ochengi adult male worm gerbil model for macrofilaricidal drug screening
PLOS Neglected Tropical Diseases: published July 1, 2019 | https://doi.org/10.1371/journal.pntd.0007556
Contrasting the value of targeted versus area-wide mosquito control scenarios to limit arbovirus transmission with human mobility patterns based on different tropical urban population centers
PLOS Neglected Tropical Diseases: published July 3, 2019 | https://doi.org/10.1371/journal.pntd.0007479
Concerns for efficacy of a 30-valent M-protein-based Streptococcus pyogenes vaccine in regions with high rates of rheumatic heart disease
PLOS Neglected Tropical Diseases: published July 3, 2019 | https://doi.org/10.1371/journal.pntd.0007511
Susceptibility of spotted doves (Streptopelia chinensis) to experimental infection with the severe fever with thrombocytopenia syndrome phlebovirus
PLOS Neglected Tropical Diseases: published July 5, 2019 | https://doi.org/10.1371/journal.pntd.0006982
Anopheles mosquito surveillance in Madagascar reveals multiple blood feeding behavior and Plasmodium infection
PLOS Neglected Tropical Diseases: published July 5, 2019 | https://doi.org/10.1371/journal.pntd.0007176
Improved assessment of mass drug administration and health district management performance to eliminate lymphatic filariasis
PLOS Neglected Tropical Diseases: published July 5, 2019 | https://doi.org/10.1371/journal.pntd.0007337
Responses of Glossina fuscipes fuscipes to visually attractive stationary devices baited with 4-methylguaiacol and certain repellent compounds in waterbuck odour
PLOS Neglected Tropical Diseases: published July 5, 2019 | https://doi.org/10.1371/journal.pntd.0007510
Potential effects of heat waves on the population dynamics of the dengue mosquito Aedes albopictus
PLOS Neglected Tropical Diseases: published July 5, 2019 | https://doi.org/10.1371/journal.pntd.0007528
Immunoproteomic analysis of a Chikungunya poxvirus-based vaccine reveals high HLA class II immunoprevalence
PLOS Neglected Tropical Diseases: published July 5, 2019 | https://doi.org/10.1371/journal.pntd.0007547
Development of multiplex PCR for neglected infectious diseases
PLOS Neglected Tropical Diseases: published July 8, 2019 | https://doi.org/10.1371/journal.pntd.0007440
The impact of acute adenolymphangitis in podoconiosis on caregivers: A case study in Wayu Tuka woreda, Oromia, Western Ethiopia. ‘If she was healthy, I would be free.’
PLOS Neglected Tropical Diseases: published July 8, 2019 | https://doi.org/10.1371/journal.pntd.0007487
Absence of accessory genes in a divergent simian T-lymphotropic virus type 1 isolated from a bonnet macaque (Macaca radiata)
PLOS Neglected Tropical Diseases: published July 8, 2019 | https://doi.org/10.1371/journal.pntd.0007521
Modelling targeted rabies vaccination strategies for a domestic dog population with heterogeneous roaming patterns
PLOS Neglected Tropical Diseases: published July 8, 2019 | https://doi.org/10.1371/journal.pntd.0007582
The monetary burden of cysticercosis in Mexico
PLOS Neglected Tropical Diseases: published July 10, 2019 | https://doi.org/10.1371/journal.pntd.0007501
Isolation and characterization of trypanosomatids, including Crithidia mellificae, in bats from the Atlantic Forest of Rio de Janeiro, Brazil
PLOS Neglected Tropical Diseases: published July 10, 2019 | https://doi.org/10.1371/journal.pntd.0007527
Detection of Crimean-Congo Haemorrhagic Fever cases in a severe undifferentiated febrile illness outbreak in the Federal Republic of Sudan: A retrospective epidemiological and diagnostic cohort study
PLOS Neglected Tropical Diseases: published July 10, 2019 | https://doi.org/10.1371/journal.pntd.0007571
Interleukin-17 and matrix metalloprotease-9 expression in the mycetoma granuloma
PLOS Neglected Tropical Diseases: published July 11, 2019 | https://doi.org/10.1371/journal.pntd.0007351
Environmental methods for dengue vector control – A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published July 11, 2019 | https://doi.org/10.1371/journal.pntd.0007420
The introduction of new hosts with human trade shapes the extant distribution of Toxoplasma gondii lineages
PLOS Neglected Tropical Diseases: published July 11, 2019 | https://doi.org/10.1371/journal.pntd.0007435
Vitamin D deficiency is a potential risk factor for lipid Amphotericin B nephrotoxicity
PLOS Neglected Tropical Diseases: published July 11, 2019 | https://doi.org/10.1371/journal.pntd.0007567
N-linked glycosylation of the West Nile virus envelope protein is not a requisite for avian virulence or vector competence
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007473
The catalytic role of a research university and international partnerships in building research capacity in Peru: A bibliometric analysis
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007483
Developing the first national database and map of lymphatic filariasis clinical cases in Bangladesh: Another step closer to the elimination goals
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007542
Genotype diversity and distribution of Mycobacterium bovis from livestock in a small, high-risk area in northeastern Sicily, Italy
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007546
Ocular immune responses, Chlamydia trachomatis infection and clinical signs of trachoma before and after azithromycin mass drug administration in a treatment naïve trachoma-endemic Tanzanian community
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007559
High-resolution contact networks of free-ranging domestic dogs Canis familiaris and implications for transmission of infection
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007565
ParaDB: A manually curated database containing genomic annotation for the human pathogenic fungi Paracoccidioides spp.
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007576
Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007578
Clinical evaluation for morbidity associated with soil-transmitted helminth infection in school-age children on Pemba Island, Tanzania
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007581
Expression of Bacillus thuringiensis toxin Cyt2Ba in the entomopathogenic fungus Beauveria bassiana increases its virulence towards Aedes mosquitoes
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007590
A nationwide survey of Leishmania infantum infection in cats and associated risk factors in Italy
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007594
The cost-effectiveness of the use of selective media for the diagnosis of melioidosis in different settings
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007598
Clinical and histopathologic features of canine tegumentary leishmaniasis and the molecular characterization of Leishmania braziliensis in dogs
PLOS Neglected Tropical Diseases: published July 16, 2019 | https://doi.org/10.1371/journal.pntd.0007532
Optimization and evaluation of the Esperanza Window Trap to reduce biting rates of Simulium damnosum sensu lato in Northern Uganda
PLOS Neglected Tropical Diseases: published July 16, 2019 | https://doi.org/10.1371/journal.pntd.0007558
Onchocerciasis-associated epilepsy in the Democratic Republic of Congo: Clinical description and relationship with microfilarial density
PLOS Neglected Tropical Diseases: published July 17, 2019 | https://doi.org/10.1371/journal.pntd.0007300
Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi
PLOS Neglected Tropical Diseases: published July 17, 2019 | https://doi.org/10.1371/journal.pntd.0007539
Dosing pole recommendations for lymphatic filariasis elimination: A height-weight quantile regression modeling approach
PLOS Neglected Tropical Diseases: published July 17, 2019 | https://doi.org/10.1371/journal.pntd.0007541
Performance of serological tests available in Brazil for the diagnosis of human visceral leishmaniasis
PLOS Neglected Tropical Diseases: published July 18, 2019 | https://doi.org/10.1371/journal.pntd.0007484
The epidemiology and clinical features of rickettsial diseases in North Queensland, Australia: Implications for patient identification and management
PLOS Neglected Tropical Diseases: published July 18, 2019 | https://doi.org/10.1371/journal.pntd.0007583
Estimating the cost of illness and burden of disease associated with the 2014–2015 chikungunya outbreak in the U.S. Virgin Islands
PLOS Neglected Tropical Diseases: published July 19, 2019 | https://doi.org/10.1371/journal.pntd.0007563
Potent and selective inhibitors for M32 metallocarboxypeptidases identified from high-throughput screening of anti-kinetoplastid chemical boxes
PLOS Neglected Tropical Diseases: published July 22, 2019 | https://doi.org/10.1371/journal.pntd.0007560
Distinguishing patients with laboratory-confirmed chikungunya from dengue and other acute febrile illnesses, Puerto Rico, 2012–2015
PLOS Neglected Tropical Diseases: published July 22, 2019 | https://doi.org/10.1371/journal.pntd.0007562
Unveil the transcriptional landscape at the Cryptococcus-host axis in mice and nonhuman primates
PLOS Neglected Tropical Diseases: published July 22, 2019 | https://doi.org/10.1371/journal.pntd.0007566
Estimated incidence and Prevalence of noma in north central Nigeria, 2010–2018: A retrospective study
PLOS Neglected Tropical Diseases: published July 22, 2019 | https://doi.org/10.1371/journal.pntd.0007574
Identification and characterization of the Onchocerca volvulus Excretory Secretory Product Ov28CRP, a putative GM2 activator protein
PLOS Neglected Tropical Diseases: published July 22, 2019 | https://doi.org/10.1371/journal.pntd.0007591
Targeting a highly repeated germline DNA sequence for improved real-time PCR-based detection of Ascaris infection in human stool
PLOS Neglected Tropical Diseases: published July 22, 2019 | https://doi.org/10.1371/journal.pntd.0007593
Serological evidence of Ebola virus exposure in dogs from affected communities in Liberia: A preliminary report
PLOS Neglected Tropical Diseases: published July 22, 2019 | https://doi.org/10.1371/journal.pntd.0007614
Insights into the genetic variation profile of tprK in Treponema pallidum during the development of natural human syphilis infection
PLOS Neglected Tropical Diseases: published July 22, 2019 | https://doi.org/10.1371/journal.pntd.0007621
Ultrasound-guided minimally invasive autopsy as a tool for rapid post-mortem diagnosis in the 2018 Sao Paulo yellow fever epidemic: Correlation with conventional autopsy
PLOS Neglected Tropical Diseases: published July 22, 2019 | https://doi.org/10.1371/journal.pntd.0007625
The effect of amantadine on an ion channel protein from Chikungunya virus
PLOS Neglected Tropical Diseases: published July 24, 2019 | https://doi.org/10.1371/journal.pntd.0007548
Autocidal gravid ovitraps protect humans from chikungunya virus infection by reducing Aedes aegypti mosquito populations
PLOS Neglected Tropical Diseases: published July 25, 2019 | https://doi.org/10.1371/journal.pntd.0007538
Genetic diversity and population structure of Glossina morsitans morsitans in the active foci of human African trypanosomiasis in Zambia and Malawi
PLOS Neglected Tropical Diseases: published July 25, 2019 | https://doi.org/10.1371/journal.pntd.0007568
The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy
PLOS Neglected Tropical Diseases: published July 25, 2019 | https://doi.org/10.1371/journal.pntd.0007589
Tracing the environmental footprint of the Burkholderia pseudomallei lipopolysaccharide genotypes in the tropical “Top End” of the Northern Territory, Australia
PLOS Neglected Tropical Diseases: published July 26, 2019 | https://doi.org/10.1371/journal.pntd.0007369
The use of chicken and insect infection models to assess the virulence of African Salmonella Typhimurium ST313
PLOS Neglected Tropical Diseases: published July 26, 2019 | https://doi.org/10.1371/journal.pntd.0007540
Cryptosporidium infection in rural Gambian children: Epidemiology and risk factors
PLOS Neglected Tropical Diseases: published July 26, 2019 | https://doi.org/10.1371/journal.pntd.0007607
Large scale detailed mapping of dengue vector breeding sites using street view images
PLOS Neglected Tropical Diseases: published July 29, 2019 | https://doi.org/10.1371/journal.pntd.0007555
Mortality by cryptococcosis in Brazil from 2000 to 2012: A descriptive epidemiological study
PLOS Neglected Tropical Diseases: published July 29, 2019 | https://doi.org/10.1371/journal.pntd.0007569
Dramatic changes in gene expression in different forms of Crithidia fasciculata reveal potential mechanisms for insect-specific adhesion in kinetoplastid parasites
PLOS Neglected Tropical Diseases: published July 29, 2019 | https://doi.org/10.1371/journal.pntd.0007570
The evolutionary dynamics of DENV 4 genotype I over a 60-year period
PLOS Neglected Tropical Diseases: published July 29, 2019 | https://doi.org/10.1371/journal.pntd.0007592
Inhibition of Ebola Virus by a Molecularly Engineered Banana Lectin
PLOS Neglected Tropical Diseases: published July 29, 2019 | https://doi.org/10.1371/journal.pntd.0007595
CXCR3 chemokine receptor guides Trypanosoma cruzi-specific T-cells triggered by DNA/adenovirus ASP2 vaccine to heart tissue after challenge
PLOS Neglected Tropical Diseases: published July 29, 2019 | https://doi.org/10.1371/journal.pntd.0007597
TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas’ heart disease
PLOS Neglected Tropical Diseases: published July 31, 2019 | https://doi.org/10.1371/journal.pntd.0007602
Corrections
Correction: DNA plasmid coding for Phlebotomus sergenti salivary protein PsSP9, a member of the SP15 family of proteins, protects against Leishmania tropica
PLOS Neglected Tropical Diseases: published July 15, 2019 | https://doi.org/10.1371/journal.pntd.0007585
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Correction: Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials
PLOS Neglected Tropical Diseases: published July 16, 2019 | https://doi.org/10.1371/journal.pntd.0007584