Great gerbils are the primary host of plague and cutaneous leismaniasis in most natural foci in Central Asia. The colonies built by these rodents are extensive, sometimes 50 meters in diameter, with the total length of the burrow systems occasionally reaching up to one kilometer. Great gerbil burrows systems play an important role in desert ecosystems, with several animal species utilizing them. Poché et al. (2018)
Image Credit: Richard M. Poché
Editorial
Global “worming”: Climate change and its projected general impact on human helminth infections
PLOS Neglected Tropical Diseases: published July 19, 2018 | https://doi.org/10.1371/journal.pntd.0006370
Viewpoints
High mortality due to snakebites in French Guiana: Time has come to re-evaluate medical management protocols
PLOS Neglected Tropical Diseases: published July 19, 2018 | https://doi.org/10.1371/journal.pntd.0006482
Snakebite envenomation in the Caribbean: The role of medical and scientific cooperation
PLOS Neglected Tropical Diseases: published July 12, 2018 | https://doi.org/10.1371/journal.pntd.0006441
Policy Platform
Genetically engineered mosquitoes, Zika and other arboviruses, community engagement, costs, and patents: Ethical issues
PLOS Neglected Tropical Diseases: published July 26, 2018 | https://doi.org/10.1371/journal.pntd.0006501
Research Articles
An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope
PLOS Neglected Tropical Diseases: published July 31, 2018 | https://doi.org/10.1371/journal.pntd.0006693
Understanding perceptions on 'Buruli' in northwestern Uganda: A biosocial investigation
PLOS Neglected Tropical Diseases: published July 30, 2018 | https://doi.org/10.1371/journal.pntd.0006689
Ecological niche modelling and predicted geographic distribution of Lutzomyia cruzi, vector of Leishmania infantum in South America
PLOS Neglected Tropical Diseases: published July 30, 2018 | https://doi.org/10.1371/journal.pntd.0006684
Differing epidemiological dynamics of Chikungunya virus in the Americas during the 2014-2015 epidemic
PLOS Neglected Tropical Diseases: published July 30, 2018 | https://doi.org/10.1371/journal.pntd.0006670
Comparing the effectiveness of different strains of Wolbachia for controlling chikungunya, dengue fever, and zika
PLOS Neglected Tropical Diseases: published July 30, 2018 | https://doi.org/10.1371/journal.pntd.0006666
A longitudinal cohort study of soil-transmitted helminth infections during the second year of life and associations with reduced long-term cognitive and verbal abilities
PLOS Neglected Tropical Diseases: published July 27, 2018 | https://doi.org/10.1371/journal.pntd.0006688
A prospective cohort study comparing household contact and water Vibrio cholerae isolates in households of cholera patients in rural Bangladesh
PLOS Neglected Tropical Diseases: published July 27, 2018 | https://doi.org/10.1371/journal.pntd.0006641
Molecular identification and antifungal susceptibility profiles of clinical strains of Fonsecaea spp. isolated from patients with chromoblastomycosis in Rio de Janeiro, Brazil
PLOS Neglected Tropical Diseases: published July 26, 2018 | https://doi.org/10.1371/journal.pntd.0006675
Molecular xenomonitoring for Wuchereria bancrofti in Culex quinquefasciatus in two districts in Bangladesh supports transmission assessment survey findings
PLOS Neglected Tropical Diseases: published July 26, 2018 | https://doi.org/10.1371/journal.pntd.0006574
Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease
PLOS Neglected Tropical Diseases: published July 25, 2018 | https://doi.org/10.1371/journal.pntd.0006687
Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series study
PLOS Neglected Tropical Diseases: published July 25, 2018 | https://doi.org/10.1371/journal.pntd.0006668
Schistosoma japonicum IAP and Teg20 safeguard tegumental integrity by inhibiting cellular apoptosis
PLOS Neglected Tropical Diseases: published July 25, 2018 | https://doi.org/10.1371/journal.pntd.0006654
A phase II study to evaluate the safety and efficacy of topical 3% amphotericin B cream (Anfoleish) for the treatment of uncomplicated cutaneous leishmaniasis in Colombia
PLOS Neglected Tropical Diseases: published July 25, 2018 | https://doi.org/10.1371/journal.pntd.0006653
Field evaluation of a 0.005% fipronil bait, orally administered to Rhombomys opimus, for control of fleas (Siphonaptera: Pulicidae) and phlebotomine sand flies (Diptera: Psychodidae) in the Central Asian Republic of Kazakhstan
PLOS Neglected Tropical Diseases: published July 25, 2018 | https://doi.org/10.1371/journal.pntd.0006630
Innate immune receptors over expression correlate with chronic chagasic cardiomyopathy and digestive damage in patients
PLOS Neglected Tropical Diseases: published July 25, 2018 | https://doi.org/10.1371/journal.pntd.0006589
Comparative proteomics of the two T. brucei PABPs suggests that PABP2 controls bulk mRNA
PLOS Neglected Tropical Diseases: published July 24, 2018 | https://doi.org/10.1371/journal.pntd.0006679
Specific human antibody responses to Aedes aegypti and Aedes polynesiensis saliva: A new epidemiological tool to assess human exposure to disease vectors in the Pacific
PLOS Neglected Tropical Diseases: published July 24, 2018 | https://doi.org/10.1371/journal.pntd.0006660
Heme crystallization in a Chagas disease vector acts as a redox-protective mechanism to allow insect reproduction and parasite infection
PLOS Neglected Tropical Diseases: published July 23, 2018 | https://doi.org/10.1371/journal.pntd.0006661
Leishmania donovani induced Unfolded Protein Response delays host cell apoptosis in PERK dependent manner
PLOS Neglected Tropical Diseases: published July 23, 2018 | https://doi.org/10.1371/journal.pntd.0006646
Systematic literature review of Rift Valley fever virus seroprevalence in livestock, wildlife and humans in Africa from 1968 to 2016
PLOS Neglected Tropical Diseases: published July 23, 2018 | https://doi.org/10.1371/journal.pntd.0006627
Classification of containers with Aedes aegypti pupae using a Neural Networks model
PLOS Neglected Tropical Diseases: published July 23, 2018 | https://doi.org/10.1371/journal.pntd.0006592
Updated evidence of the association between toxocariasis and epilepsy: Systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published July 20, 2018 | https://doi.org/10.1371/journal.pntd.0006665
Epidemiology and morbidity of hookworm-related cutaneous larva migrans (HrCLM): Results of a cohort study over a period of six months in a resource-poor community in Manaus, Brazil
PLOS Neglected Tropical Diseases: published July 19, 2018 | https://doi.org/10.1371/journal.pntd.0006662
Towards a science of global health delivery: A socio-anthropological framework to improve the effectiveness of neglected tropical disease interventions
PLOS Neglected Tropical Diseases: published July 19, 2018 | https://doi.org/10.1371/journal.pntd.0006537
Determinants for not utilizing trachomatous trichiasis surgery among trachomatous trichiasis patients in Mehalsayint District, North-East Ethiopia
PLOS Neglected Tropical Diseases: published July 18, 2018 | https://doi.org/10.1371/journal.pntd.0006669
Peripheral nerve abnormality in HIV leprosy patients
PLOS Neglected Tropical Diseases: published July 18, 2018 | https://doi.org/10.1371/journal.pntd.0006633
Combining Wolbachia-induced sterility and virus protection to fight Aedes albopictus-borne viruses
PLOS Neglected Tropical Diseases: published July 18, 2018 | https://doi.org/10.1371/journal.pntd.0006626
Zika virus outbreak in the Pacific: Vector competence of regional vectors
PLOS Neglected Tropical Diseases: published July 17, 2018 | https://doi.org/10.1371/journal.pntd.0006637
Grade 2 disabilities in leprosy patients from Brazil: Need for follow-up after completion of multidrug therapy
PLOS Neglected Tropical Diseases: published July 16, 2018 | https://doi.org/10.1371/journal.pntd.0006645
Study on causes of fever in primary healthcare center uncovers pathogens of public health concern in Madagascar
PLOS Neglected Tropical Diseases: published July 16, 2018 | https://doi.org/10.1371/journal.pntd.0006642
Heterogeneity of Orientia tsutsugamushi genotypes in field-collected trombiculid mites from wild-caught small mammals in Thailand
PLOS Neglected Tropical Diseases: published July 16, 2018 | https://doi.org/10.1371/journal.pntd.0006632
Nucleocapsid protein-based vaccine provides protection in mice against lethal Crimean-Congo hemorrhagic fever virus challenge
PLOS Neglected Tropical Diseases: published July 16, 2018 | https://doi.org/10.1371/journal.pntd.0006628
Dengue infection in India: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published July 16, 2018 | https://doi.org/10.1371/journal.pntd.0006618
Evidence of vertical transmission of Zika virus in field-collected eggs of Aedes aegypti in the Brazilian Amazon
PLOS Neglected Tropical Diseases: published July 16, 2018 | https://doi.org/10.1371/journal.pntd.0006594
Identifying residual transmission of lymphatic filariasis after mass drug administration: Comparing school-based versus community-based surveillance - American Samoa, 2016
PLOS Neglected Tropical Diseases: published July 16, 2018 | https://doi.org/10.1371/journal.pntd.0006583
Current challenges and implications for dengue, chikungunya and Zika seroprevalence studies worldwide: A scoping review
PLOS Neglected Tropical Diseases: published July 16, 2018 | https://doi.org/10.1371/journal.pntd.0006533
Nitrosporeusine analogue ameliorates Chandipura virus induced inflammatory response in CNS via NFκb inactivation in microglia
PLOS Neglected Tropical Diseases: published July 12, 2018 | https://doi.org/10.1371/journal.pntd.0006648
Clinical, environmental, and behavioral characteristics associated with Cryptosporidium infection among children with moderate-to-severe diarrhea in rural western Kenya, 2008–2012: The Global Enteric Multicenter Study (GEMS)
PLOS Neglected Tropical Diseases: published July 12, 2018 | https://doi.org/10.1371/journal.pntd.0006640
Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays
PLOS Neglected Tropical Diseases: published July 12, 2018 | https://doi.org/10.1371/journal.pntd.0006639
Animal influence on water, sanitation and hygiene measures for zoonosis control at the household level: A systematic literature review
PLOS Neglected Tropical Diseases: published July 12, 2018 | https://doi.org/10.1371/journal.pntd.0006619
Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas’ disease drug discovery
PLOS Neglected Tropical Diseases: published July 12, 2018 | https://doi.org/10.1371/journal.pntd.0006612
Revisiting the concept of Innovative Developing Countries (IDCs) for its relevance to health innovation and neglected tropical diseases and for the prevention and control of epidemics
PLOS Neglected Tropical Diseases: published July 12, 2018 | https://doi.org/10.1371/journal.pntd.0006469
2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm
PLOS Neglected Tropical Diseases: published July 11, 2018 | https://doi.org/10.1371/journal.pntd.0006487
Snakebite incidence in two townships in Mandalay Division, Myanmar
PLOS Neglected Tropical Diseases: published July 9, 2018 | https://doi.org/10.1371/journal.pntd.0006643
Socioeconomic risk markers of leprosy in high-burden countries: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published July 9, 2018 | https://doi.org/10.1371/journal.pntd.0006622
Epitope-mapping of the glycoprotein from Crimean-Congo hemorrhagic fever virus using a microarray approach
PLOS Neglected Tropical Diseases: published July 9, 2018 | https://doi.org/10.1371/journal.pntd.0006598
Both living bacteria and eukaryotes in the mosquito gut promote growth of larvae
PLOS Neglected Tropical Diseases: published July 6, 2018 | https://doi.org/10.1371/journal.pntd.0006638
The current epidemiological status of urogenital schistosomiasis among primary school pupils in Katsina State, Nigeria: An imperative for a scale up of water and sanitation initiative and mass administration of medicines with Praziquantel
PLOS Neglected Tropical Diseases: published July 6, 2018 | https://doi.org/10.1371/journal.pntd.0006636
Characterization of the microtranscriptome of macrophages infected with virulent, attenuated and saprophyte strains of Leptospira spp.
PLOS Neglected Tropical Diseases: published July 6, 2018 | https://doi.org/10.1371/journal.pntd.0006621
Genetic diversity, phylogeography and molecular clock of the Lutzomyia longipalpis complex (Diptera: Psychodidae)
PLOS Neglected Tropical Diseases: published July 5, 2018 | https://doi.org/10.1371/journal.pntd.0006614
Multilocus microsatellite typing (MLMT) reveals host-related population structure in Leishmania infantum from northeastern Italy
PLOS Neglected Tropical Diseases: published July 5, 2018 | https://doi.org/10.1371/journal.pntd.0006595
Impact of a national deworming campaign on the prevalence of soil-transmitted helminthiasis in Uganda (2004-2016): Implications for national control programs
PLOS Neglected Tropical Diseases: published July 5, 2018 | https://doi.org/10.1371/journal.pntd.0006520
The spleen microbiota of small wild mammals reveals distinct patterns with tick-borne bacteria
PLOS Neglected Tropical Diseases: published July 5, 2018 | https://doi.org/10.1371/journal.pntd.0006499
Impact of schistosome infection on long-term HIV/AIDS outcomes
PLOS Neglected Tropical Diseases: published July 2, 2018 | https://doi.org/10.1371/journal.pntd.0006613
Diagnosis and impact of neuropathic pain in leprosy patients in Nepal after completion of multidrug therapy
PLOS Neglected Tropical Diseases: published July 2, 2018 | https://doi.org/10.1371/journal.pntd.0006610
Vitamin D status contributes to the antimicrobial activity of macrophages against Mycobacterium leprae
PLOS Neglected Tropical Diseases: published July 2, 2018 | https://doi.org/10.1371/journal.pntd.0006608
Non-randomized controlled trial of the long-term efficacy of an Ecohealth intervention against Chagas disease in Yucatan, Mexico
PLOS Neglected Tropical Diseases: published July 2, 2018 | https://doi.org/10.1371/journal.pntd.0006605
Variation in competence for ZIKV transmission by Aedes aegypti and Aedes albopictus in Mexico
PLOS Neglected Tropical Diseases: published July 2, 2018 | https://doi.org/10.1371/journal.pntd.0006599
Domestic animals infected with Mycobacterium ulcerans—Implications for transmission to humans
PLOS Neglected Tropical Diseases: published July 2, 2018 | https://doi.org/10.1371/journal.pntd.0006572
Integrated morbidity mapping of lymphatic filariasis and podoconiosis cases in 20 co-endemic districts of Ethiopia
PLOS Neglected Tropical Diseases: published July 2, 2018 | https://doi.org/10.1371/journal.pntd.0006491