Table of Contents

December 2015

Scabies was previously endemic in the communities of the Lau Lagoon in the Solomon Islands. An intensive control program between 1997–2000 using ivermectin resulted in a dramatic decline in the prevalence of both scabies and secondary bacterial infections. A follow-up survey conducted in 2015 found that long term control of scabies had been achieved in these communities. Marks et al.

Image Credit: Michael Marks


The 1899 United States Kissing Bug Epidemic

Melissa N. Garcia, Daisy Hernandez, Rodion Gorchakov, Kristy O. Murray, Peter J. Hotez


Trachoma and Yaws: Common Ground?

Anthony W. Solomon, Michael Marks, Diana L. Martin, Alexei Mikhailov, Rebecca M. Flueckiger, Oriol Mitjà, Kingsley Asiedu, Jean Jannin, Dirk Engels, David C. W. Mabey


A Spatiotemporal Database to Track Human Scrub Typhus Using the VectorMap Application

Daryl J. Kelly, Desmond H. Foley, Allen L. Richards

Earth Observation, Spatial Data Quality, and Neglected Tropical Diseases

Nicholas A. S. Hamm, Ricardo J. Soares Magalhães, Archie C. A. Clements

Assessing “First Mile” Supply Chain Factors Affecting Timeliness of School-Based Deworming Interventions: Supply and Logistics Performance Indicators

Kimberly M. Koporc, Eric Strunz, Cassandra Holloway, David G. Addiss, William Lin

The Interplay of Host Microbiota and Parasitic Protozoans at Mucosal Interfaces: Implications for the Outcomes of Infections and Diseases

Ann-Katrein Bär, Niha Phukan, Jully Pinheiro, Augusto Simoes-Barbosa

A Review of the Role of Food and the Food System in the Transmission and Spread of Ebolavirus

Erin Mann, Stephen Streng, Justin Bergeron, Amy Kircher

Research Articles

Using Co-authorship Networks to Map and Analyse Global Neglected Tropical Disease Research with an Affiliation to Germany

Max Ernst Bender, Suzanne Edwards, Peter von Philipsborn, Fridolin Steinbeis, Thomas Keil, Peter Tinnemann

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Plasmodium malariae Infection Associated with a High Burden of Anemia: A Hospital-Based Surveillance Study

Siobhan Langford, Nicholas M. Douglas, Daniel A. Lampah, Julie A. Simpson, Enny Kenangalem, Paulus Sugiarto, Nicholas M. Anstey, Jeanne Rini Poespoprodjo, Ric N. Price

Glycans from Fasciola hepatica Modulate the Host Immune Response and TLR-Induced Maturation of Dendritic Cells

Ernesto Rodríguez, Verónica Noya, Laura Cervi, María Laura Chiribao, Natalie Brossard, Carolina Chiale, Carlos Carmona, Cecilia Giacomini, Teresa Freire

Quantifying Poverty as a Driver of Ebola Transmission

Mosoka P. Fallah, Laura A. Skrip, Shai Gertler, Dan Yamin, Alison P. Galvani

Trichinella spiralis Paramyosin Binds Human Complement C1q and Inhibits Classical Complement Activation

Ran Sun, Xi Zhao, Zixia Wang, Jing Yang, Limei Zhao, Bin Zhan, Xinping Zhu

Molecular Detection of Schistosome Infections with a Disposable Microfluidic Cassette

Jinzhao Song, Changchun Liu, Swarna Bais, Michael G. Mauk, Haim H. Bau, Robert M. Greenberg

Schistosoma mansoni Egg, Adult Male and Female Comparative Gene Expression Analysis and Identification of Novel Genes by RNA-Seq

Letícia Anderson, Murilo S. Amaral, Felipe Beckedorff, Lucas F. Silva, Bianca Dazzani, Katia C. Oliveira, Giulliana T. Almeida, Monete R. Gomes, David S. Pires, João C. Setubal, Ricardo DeMarco, Sergio Verjovski-Almeida

Pregnancy Outcomes after a Mass Vaccination Campaign with an Oral Cholera Vaccine in Guinea: A Retrospective Cohort Study

Lise Grout, Isabel Martinez-Pino, Iza Ciglenecki, Sakoba Keita, Alpha Amadou Diallo, Balla Traore, Daloka Delamou, Oumar Toure, Sarala Nicholas, Barbara Rusch, Nelly Staderini, Micaela Serafini, Rebecca F. Grais, Francisco J. Luquero

The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development

Peter D. Ziniel, Bhargava Karumudi, Andrew H. Barnard, Ethan M. S. Fisher, Gregory R. J. Thatcher, Larissa M. Podust, David L. Williams

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Whole Genome Sequencing of Field Isolates Reveals Extensive Genetic Diversity in Plasmodium vivax from Colombia

David J. Winter, M. Andreína Pacheco, Andres F. Vallejo, Rachel S. Schwartz, Myriam Arevalo-Herrera, Socrates Herrera, Reed A. Cartwright, Ananias A. Escalante

Cissampelos pareira Linn: Natural Source of Potent Antiviral Activity against All Four Dengue Virus Serotypes

Ruchi Sood, Rajendra Raut, Poornima Tyagi, Pawan Kumar Pareek, Tarani Kanta Barman, Smita Singhal, Raj Kumar Shirumalla, Vijay Kanoje, Ramesh Subbarayan, Ravisankar Rajerethinam, Navin Sharma, Anil Kanaujia, Gyanesh Shukla, Y. K. Gupta, Chandra K. Katiyar, Pradip K. Bhatnagar, Dilip J. Upadhyay, Sathyamangalam Swaminathan, Navin Khanna

A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions

Jessica B. Hostetler, Sumana Sharma, S. Josefin Bartholdson, Gavin J. Wright, Rick M. Fairhurst, Julian C. Rayner

Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis

Elisangela Oliveira Freitas, Dirlei Nico, Marcus Vinícius Alves-Silva, Alexandre Morrot, Keith Clinch, Gary B. Evans, Peter C. Tyler, Vern L. Schramm, Clarisa B. Palatnik-de-Sousa

Identification and Characterization of Microsatellite Markers Derived from the Whole Genome Analysis of Taenia solium

Mónica J. Pajuelo, María Eguiluz, Eric Dahlstrom, David Requena, Frank Guzmán, Manuel Ramirez, Patricia Sheen, Michael Frace, Scott Sammons, Vitaliano Cama, Sarah Anzick, Dan Bruno, Siddhartha Mahanty, Patricia Wilkins, Theodore Nash, Armando Gonzalez, Héctor H. García, Robert H. Gilman, Steve Porcella, Mirko Zimic, Cysticercosis Working Group in Peru

The Risk of Nosocomial Transmission of Rift Valley Fever

Nasser A. Al-Hamdan, Anil A. Panackal, Tami H. Al Bassam, Abdullah Alrabea, Mohammed Al Hazmi, Yagoub Al Mazroa, Mohammed Al Jefri, Ali S. Khan, Thomas G. Ksiazek

Generation of a Novel Bacteriophage Library Displaying scFv Antibody Fragments from the Natural Buffalo Host to Identify Antigens from Adult Schistosoma japonicum for Diagnostic Development

Christopher G. Hosking, Hamish E. G. McWilliam, Patrick Driguez, David Piedrafita, Yuesheng Li, Donald P. McManus, Leodevico L. Ilag, Els N. T. Meeusen, Michael J. de Veer

Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome

Deuan C. Jones, Bernardo J. Foth, Michael D. Urbaniak, Stephen Patterson, Han B. Ong, Matthew Berriman, Alan H. Fairlamb

Peridomestic Infection as a Determining Factor of Dengue Transmission

Ruth Aralí Martínez-Vega, Rogelio Danis-Lozano, Fredi Alexander Díaz-Quijano, Jorge Velasco-Hernández, René Santos-Luna, Susana Román-Pérez, Pablo Kuri-Morales, José Ramos-Castañeda

Inflammation Caused by Praziquantel Treatment Depends on the Location of the Taenia solium Cysticercus in Porcine Neurocysticercosis

Carla Cangalaya, Mirko Zimic, Miguel Marzal, Armando E. González, Cristina Guerra-Giraldez, Siddhartha Mahanty, Theodore E. Nash, Hector H. García, Cysticercosis Working Group in Peru

Stakeholder Narratives on Trypanosomiasis, Their Effect on Policy and the Scope for One Health

Catherine Grant, Neil Anderson, Noreen Machila

Epidemiology of Infant Dengue Cases Illuminates Serotype-Specificity in the Interaction between Immunity and Disease, and Changes in Transmission Dynamics

Hannah Clapham, Derek A. T. Cummings, Ananda Nisalak, Siripen Kalayanarooj, Butsaya Thaisomboonsuk, Chonticha Klungthong, Stefan Fernandez, Anon Srikiatkhachorn, Louis R. Macareo, Justin Lessler, Julia Reiser, In-Kyu Yoon

Coevolution of the Ile1,016 and Cys1,534 Mutations in the Voltage Gated Sodium Channel Gene of Aedes aegypti in Mexico

Farah Z. Vera-Maloof, Karla Saavedra-Rodriguez, Armando E. Elizondo-Quiroga, Saul Lozano-Fuentes, William C. Black IV

Assessment of a Novel Approach to Identify Trichiasis Cases Using Community Treatment Assistants in Tanzania

Gregory S. Greene, Sheila K. West, Harran Mkocha, Beatriz Munoz, Shannath L. Merbs

Parasitological Confirmation and Analysis of Leishmania Diversity in Asymptomatic and Subclinical Infection following Resolution of Cutaneous Leishmaniasis

Mariana Rosales-Chilama, Rafael E. Gongora, Liliana Valderrama, Jimena Jojoa, Neal Alexander, Luisa C. Rubiano, Alexandra Cossio, Emily R. Adams, Nancy G. Saravia, María Adelaida Gomez

Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni

Swarna Bais, Matthew A. Churgin, Christopher Fang-Yen, Robert M. Greenberg

Combining Public Health Education and Disease Ecology Research: Using Citizen Science to Assess Chagas Disease Entomological Risk in Texas

Rachel Curtis-Robles, Edward J. Wozniak, Lisa D. Auckland, Gabriel L. Hamer, Sarah A. Hamer

Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus

Patrícia de Sousa Lima, Dawoon Chung, Alexandre Melo Bailão, Robert A. Cramer, Célia Maria de Almeida Soares

Expression of Trypanosoma brucei gambiense Antigens in Leishmania tarentolae. Potential for Use in Rapid Serodiagnostic Tests (RDTs)

Barrie Rooney, Turid Piening, Philippe Büscher, Stijn Rogé, C. Mark Smales

Cooperation between CD4+ T Cells and Humoral Immunity Is Critical for Protection against Dengue Using a DNA Vaccine Based on the NS1 Antigen

Antônio J. S. Gonçalves, Edson R. A. Oliveira, Simone M. Costa, Marciano V. Paes, Juliana F. A. Silva, Adriana S. Azevedo, Marcio Mantuano-Barradas, Ana Cristina M. A. Nogueira, Cecília J. Almeida, Ada M. B. Alves

Comparison of Leishmania killicki (syn. L. tropica) and Leishmania tropica Population Structure in Maghreb by Microsatellite Typing

Dhekra Chaara, Anne- Laure Bañuls, Najoua Haouas, Loïc Talignani, Patrick Lami, Habib Mezhoud, Zoubir Harrat, Jean-Pierre Dedet, Hamouda Babba, Francine Pratlong

Cloning and Characterization of Two Potent Kunitz Type Protease Inhibitors from Echinococcus granulosus

Shiwanthi L. Ranasinghe, Katja Fischer, Wenbao Zhang, Geoffrey N. Gobert, Donald P. McManus

Asymmetric Nerve Enlargement: A Characteristic of Leprosy Neuropathy Demonstrated by Ultrasonography

Helena Barbosa Lugão, Marcello Henrique Nogueira-Barbosa, Wilson Marques Jr., Norma Tiraboschi Foss, Marco Andrey Cipriani Frade

Tracking Cholera through Surveillance of Oral Rehydration Solution Sales at Pharmacies: Insights from Urban Bangladesh

Andrew S. Azman, Justin Lessler, Syed Moinuddin Satter, Michael V. Mckay, Azharul Khan, Dilruba Ahmed, Emily S. Gurley

Molecular Differentiation of the African Yellow Fever Vector Aedes bromeliae (Diptera: Culicidae) from Its Sympatric Non-vector Sister Species, Aedes lilii

Kelly Louise Bennett, Yvonne-Marie Linton, Fortunate Shija, Martha Kaddumukasa, Rousseau Djouaka, Gerald Misinzo, Julius Lutwama, Yiau-Min Huang, Luke B. Mitchell, Miriam Richards, Eric Tossou, Catherine Walton

The Schistosome Esophagus Is a ‘Hotspot’ for Microexon and Lysosomal Hydrolase Gene Expression: Implications for Blood Processing

R. Alan Wilson, Xiao Hong Li, Sandy MacDonald, Leandro Xavier Neves, Juliana Vitoriano-Souza, Luciana C. C. Leite, Leonardo P. Farias, Sally James, Peter D. Ashton, Ricardo DeMarco, William Castro Borges

Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites

Brendan R. E. Ansell, Malcolm J. McConville, Louise Baker, Pasi K. Korhonen, Neil D. Young, Ross S. Hall, Cristian A. A. Rojas, Staffan G. Svärd, Robin B. Gasser, Aaron R. Jex

The Pattern of Adipose Tissue Accumulation during Early Infancy Provides an Environment for the Development of Dengue Hemorrhagic Fever

Daniel H. Libraty, Pengyan Wang, Zhiru Guo, Venelle Bigcas, Job D. Brion, Rosario Z. Capeding

Environmental Transmission of Typhoid Fever in an Urban Slum

Adam Akullian, Eric Ng’eno, Alastair I. Matheson, Leonard Cosmas, Daniel Macharia, Barry Fields, Godfrey Bigogo, Maina Mugoh, Grace John-Stewart, Judd L. Walson, Jonathan Wakefield, Joel M. Montgomery

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Long Term Control of Scabies Fifteen Years after an Intensive Treatment Programme

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