Indonesia: An Emerging Market Economy Beset by Neglected Tropical Diseases (NTDs)

Melody Tan, Rita Kusriastuti, Lorenzo Savioli, Peter J. Hotez

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002449

Detection Of Four Dengue Serotypes Suggests Rise In Hyperendemicity In Urban Centers Of Brazil

Christian Julián Villabona-Arenas, Jessica Luana de Oliveira, Carla de Sousa Capra, Karime Balarini, Mauricio Loureiro, Celso Ricardo Theoto P. Fonseca, Saulo Duarte Passos, Paolo Marinho de Andrade Zanotto

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002620

Odile Bain (April 28, 1939–October 16, 2012): A Life Dedicated to Systematics and Biology of Filariae

Coralie Martin

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002565

Resource Planning for Neglected Tropical Disease (NTD) Control Programs: Feasibility Study of the Tool for Integrated Planning and Costing (TIPAC)

Olivier J. Wouters, Philip W. Downs, Kathryn L. Zoerhoff, Kathryn R. Crowley, Hannah Frawley, Jennifer Einberg, Brian K. Chu, Molly A. Brady, Roland Oscar, Mireille Jeudi, Anne-Marie Desormeaux, Karleen Coly, Abdel N. Direny, Garib D. Thakur, Raj K. Pokharel, Shekhar Sharma, Dharmpal P. Raman, Santigie Sesay, Mustapha Sonnie, Bernard Kilembe, Upendo Mwingira, Aya Yajima

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002619

On the Age of Leprosy

Xiang Y. Han, Francisco J. Silva

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002544

Impairment of T Cell Function in Parasitic Infections

Vasco Rodrigues, Anabela Cordeiro-da-Silva, Mireille Laforge, Ali Ouaissi, Khadija Akharid, Ricardo Silvestre, Jérôme Estaquier

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002567

A Multi-species Bait for Chagas Disease Vectors

Theo Mota, Ana C. R. Vitta, Alicia N. Lorenzo-Figueiras, Carla P. Barezani, Carlos L. Zani, Claudio R. Lazzari, Liléia Diotaiuti, Lynne Jeffares, Björn Bohman, Marcelo G. Lorenzo

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002677

Comparative Analysis of Salivary Gland Transcriptomes of Phlebotomus orientalis Sand Flies from Endemic and Non-endemic Foci of Visceral Leishmaniasis

Michaela Vlkova, Michal Sima, Iva Rohousova, Tatiana Kostalova, Petra Sumova, Vera Volfova, Erin L. Jaske, Kent D. Barbian, Teshome Gebre-Michael, Asrat Hailu, Alon Warburg, Jose M. C. Ribeiro, Jesus G. Valenzuela, Ryan C. Jochim, Petr Volf

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002709

Evaluation of Internet-Based Dengue Query Data: Google Dengue Trends

Rebecca Tave Gluskin, Michael A. Johansson, Mauricio Santillana, John S. Brownstein

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002713

Memantine, an Antagonist of the NMDA Glutamate Receptor, Affects Cell Proliferation, Differentiation and the Intracellular Cycle and Induces Apoptosis in Trypanosoma cruzi

Flávia Silva Damasceno, María Julia Barisón, Elisabeth Mieko Furusho Pral, Lisvane Silva Paes, Ariel Mariano Silber

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002717

Risk Factors for Soil-Transmitted Helminth Infections during the First 3 Years of Life in the Tropics; Findings from a Birth Cohort

Stefanie K. Menzies, Alejandro Rodriguez, Martha Chico, Carlos Sandoval, Nely Broncano, Irene Guadalupe, Philip J. Cooper

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002718

Costs Analysis of a Population Level Rabies Control Programme in Tamil Nadu, India

Syed Shahid Abbas, Manish Kakkar, Elizabeth Tacket Rogawski, on behalf of the Roadmap to Combat Zoonoses in India (RCZI) initiative

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002721

Pharmacological Approaches That Slow Lymphatic Flow As a Snakebite First Aid

Dirk F. van Helden, Paul A. Thomas, Peter J. Dosen, Mohammad S. Imtiaz, Derek R. Laver, Geoffrey K. Isbister

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002722

The Association of Parasitic Infections in Pregnancy and Maternal and Fetal Anemia: A Cohort Study in Coastal Kenya

Elizabeth M. McClure, Steven R. Meshnick, Peter Mungai, Indu Malhotra, Christopher L. King, Robert L. Goldenberg, Michael G. Hudgens, Anna Maria Siega-Riz, Arlene E. Dent

PLOS Neglected Tropical Diseases: published February 27, 2014 | https://doi.org/10.1371/journal.pntd.0002724

A Polarized Cell Model for Chikungunya Virus Infection: Entry and Egress of Virus Occurs at the Apical Domain of Polarized Cells

Pei Jin Lim, Justin Jang Hann Chu

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002661

Significantly Lower Anti-Leishmania IgG Responses in Sudanese versus Indian Visceral Leishmaniasis

Tapan Bhattacharyya, Duncan E. Bowes, Sayda El-Safi, Shyam Sundar, Andrew K. Falconar, Om Prakash Singh, Rajiv Kumar, Osman Ahmed, Marleen Boelaert, Michael A. Miles

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002675

Immunoepidemiological Profiling of Onchocerciasis Patients Reveals Associations with Microfilaria Loads and Ivermectin Intake on Both Individual and Community Levels

Kathrin Arndts, Sabine Specht, Alexander Y. Debrah, Francesca Tamarozzi, Ute Klarmann Schulz, Sabine Mand, Linda Batsa, Alexander Kwarteng, Mark Taylor, Ohene Adjei, Coralie Martin, Laura E. Layland, Achim Hoerauf

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002679

Limited Dengue Virus Replication in Field-Collected Aedes aegypti Mosquitoes Infected with Wolbachia

Francesca D. Frentiu, Tasnim Zakir, Thomas Walker, Jean Popovici, Alyssa T. Pyke, Andrew van den Hurk, Elizabeth A. McGraw, Scott L. O'Neill

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002688

Efficacy of Cyclooctadepsipeptides and Aminophenylamidines against Larval, Immature and Mature Adult Stages of a Parasitologically Characterized Trichurosis Model in Mice

Daniel Kulke, Jürgen Krücken, Achim Harder, Georg von Samson-Himmelstjerna

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002698

Parasite-Derived MicroRNAs in Host Serum As Novel Biomarkers of Helminth Infection

Anna M. Hoy, Rachel J. Lundie, Alasdair Ivens, Juan F. Quintana, Norman Nausch, Thorsten Forster, Frances Jones, Narcis B. Kabatereine, David W. Dunne, Francisca Mutapi, Andrew S. MacDonald, Amy H. Buck

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002701

Deletion of Ubiquitin Fold Modifier Protein Ufm1 Processing Peptidase Ufsp in L. donovani Abolishes Ufm1 Processing and Alters Pathogenesis

Sreenivas Gannavaram, Sonya Davey, Ines Lakhal-Naouar, Robert Duncan, Hira L. Nakhasi

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002707

Predictive Value of Proteinuria in Adult Dengue Severity

Farhad F. Vasanwala, Tun-Linn Thein, Yee-Sin Leo, Victor C. Gan, Ying Hao, Linda K. Lee, David C. Lye

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002712

Mapping the Geographical Distribution of Lymphatic Filariasis in Zambia

Enala T. Mwase, Anna-Sofie Stensgaard, Mutale Nsakashalo-Senkwe, Likezo Mubila, James Mwansa, Peter Songolo, Sheila T. Shawa, Paul E. Simonsen

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002714

Comparison of Three Quality of Life Instruments in Lymphatic Filariasis: DLQI, WHODAS 2.0, and LFSQQ

Cristina Thomas, Saravu R. Narahari, Kuthaje S. Bose, Kuthaje Vivekananda, Steven Nwe, Dennis P. West, Mary Kwasny, Roopal V. Kundu

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002716

Deliberate Attenuation of Chikungunya Virus by Adaptation to Heparan Sulfate-Dependent Infectivity: A Model for Rational Arboviral Vaccine Design

Christina L. Gardner, Jozef Hritz, Chengqun Sun, Dana L. Vanlandingham, Timothy Y. Song, Elodie Ghedin, Stephen Higgs, William B. Klimstra, Kate D. Ryman

PLOS Neglected Tropical Diseases: published February 20, 2014 | https://doi.org/10.1371/journal.pntd.0002719

Adult Survivorship of the Dengue Mosquito Aedes aegypti Varies Seasonally in Central Vietnam

Leon E. Hugo, Jason A. L. Jeffery, Brendan J. Trewin, Leesa F. Wockner, Nguyen Thi Yen, Nguyen Hoang Le, Le Trung Nghia, Emma Hine, Peter A. Ryan, Brian H. Kay

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002669

Deletion of the NSm Virulence Gene of Rift Valley Fever Virus Inhibits Virus Replication in and Dissemination from the Midgut of Aedes aegypti Mosquitoes

Rebekah C. Kading, Mary B. Crabtree, Brian H. Bird, Stuart T. Nichol, Bobbie Rae Erickson, Kalanthe Horiuchi, Brad J. Biggerstaff, Barry R. Miller

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002670

Antidiarrheal Efficacy and Cellular Mechanisms of a Thai Herbal Remedy

Lukmanee Tradtrantip, Eun-A Ko, Alan S. Verkman

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002674

Computational Studies on Sirtuins from Trypanosoma cruzi: Structures, Conformations and Interactions with Phytochemicals

Lionel Sacconnay, Melissa Angleviel, Giuseppe Marco Randazzo, Marcos Marçal Ferreira Queiroz, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Pierre-Alain Carrupt, Alessandra Nurisso

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002689

Neurocysticercosis as a Cause of Epilepsy and Seizures in Two Community-Based Studies in a Cysticercosis-Endemic Region in Peru

Luz M. Moyano, Mayuko Saito, Silvia M. Montano, Guillermo Gonzalvez, Sandra Olaya, Viterbo Ayvar, Isidro González, Luis Larrauri, Victor C. W. Tsang, Fernando Llanos, Silvia Rodríguez, Armando E. Gonzalez, Robert H. Gilman, Hector H. Garcia, for The Cysticercosis Working Group in Peru

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002692

Molecular, Immunological, and Biological Characterization of Tityus serrulatus Venom Hyaluronidase: New Insights into Its Role in Envenomation

Carolina Campolina Rebello Horta, Bárbara de Freitas Magalhães, Bárbara Bruna Ribeiro Oliveira-Mendes, Anderson Oliveira do Carmo, Clara Guerra Duarte, Liza Figueiredo Felicori, Ricardo Andrez Machado-de-Ávila, Carlos Chávez-Olórtegui, Evanguedes Kalapothakis

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002693

Rapid Healing of Cutaneous Leishmaniasis by High-Frequency Electrocauterization and Hydrogel Wound Care with or without DAC N-055: A Randomized Controlled Phase IIa Trial in Kabul

Ahmad Fawad Jebran, Ulrike Schleicher, Reto Steiner, Pia Wentker, Farouq Mahfuz, Hans-Christian Stahl, Faquir Mohammad Amin, Christian Bogdan, Kurt-Wilhelm Stahl

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002694

Multilocus Sequence Analysis for Leishmania braziliensis Outbreak Investigation

Mariel A. Marlow, Mariana C. Boité, Gabriel Eduardo M. Ferreira, Mario Steindel, Elisa Cupolillo

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002695

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Fernando J. Sánchez-Valdéz, Cecilia Pérez Brandán, Galia Ramírez, Alejandro D. Uncos, M. Paola Zago, Rubén O. Cimino, Rubén M. Cardozo, Jorge D. Marco, Arturo Ferreira, Miguel Ángel Basombrío

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Laboratory Colonisation and Genetic Bottlenecks in the Tsetse Fly Glossina pallidipes

Marc Ciosi, Daniel K. Masiga, Charles M. R. Turner

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002697

A Repurposing Strategy for Hsp90 Inhibitors Demonstrates Their Potency against Filarial Nematodes

Victoria Gillan, Kerry O'Neill, Kirsty Maitland, Francis M. Sverdrup, Eileen Devaney

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002699

Determinants of Heterogeneous Blood Feeding Patterns by Aedes aegypti in Iquitos, Peru

Kelly A. Liebman, Steven T. Stoddard, Robert C. Reiner Jr, T. Alex Perkins, Helvio Astete, Moises Sihuincha, Eric S. Halsey, Tadeusz J. Kochel, Amy C. Morrison, Thomas W. Scott

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002702

Schistosoma japonicum Egg Specific Protein SjE16.7 Recruits Neutrophils and Induces Inflammatory Hepatic Granuloma Initiation

Chenyun Wu, Qing Chen, Yan Fang, Jianhua Wu, Yanyan Han, Ying Wang, Yang Yang, Min Chu, Yan Feng, Linping Tan, Xiaokui Guo, Wei Hu, Zhaojun Wang

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002703

Incorporating Scale Dependence in Disease Burden Estimates: The Case of Human African Trypanosomiasis in Uganda

Finola Hackett, Lea Berrang Ford, Eric Fèvre, Pere Simarro

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002704

Estimating Diarrheal Illness and Deaths Attributable to Shigellae and Enterotoxigenic Escherichia coli among Older Children, Adolescents, and Adults in South Asia and Africa

Laura M. Lamberti, A. Louis Bourgeois, Christa L. Fischer Walker, Robert E. Black, David Sack

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002705

Serological Evidence of Widespread Circulation of West Nile Virus and Other Flaviviruses in Equines of the Pantanal, Brazil

Alex Pauvolid-Corrêa, Zilca Campos, Raquel Juliano, Jason Velez, Rita Maria Ribeiro Nogueira, Nicholas Komar

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002706

Pilot Assessment of Soil-Transmitted Helminthiasis in the Context of Transmission Assessment Surveys for Lymphatic Filariasis in Benin and Tonga

Brian K. Chu, Katherine Gass, Wilfrid Batcho, Malakai 'Ake, Améyo M. Dorkenoo, Elvire Adjinacou, 'Eva Mafi, David G. Addiss

PLOS Neglected Tropical Diseases: published February 13, 2014 | https://doi.org/10.1371/journal.pntd.0002708

Mass Vaccination with a New, Less Expensive Oral Cholera Vaccine Using Public Health Infrastructure in India: The Odisha Model

Shantanu K. Kar, Binod Sah, Bikash Patnaik, Yang Hee Kim, Anna S. Kerketta, Sunheang Shin, Shyam Bandhu Rath, Mohammad Ali, Vittal Mogasale, Hemant K. Khuntia, Anuj Bhattachan, Young Ae You, Mahesh K. Puri, Anna Lena Lopez, Brian Maskery, Gopinath B. Nair, John D. Clemens, Thomas F. Wierzba

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002629

First Detection of Leishmania tropica DNA and Trypanosoma Species in Sergentomyia Sand Flies (Diptera: Psychodidae) from an Outbreak Area of Cutaneous Leishmaniasis in Ghana

Chukwunonso O. Nzelu, Hirotomo Kato, Naiki Puplampu, Kwame Desewu, Shirley Odoom, Michael D. Wilson, Tatsuya Sakurai, Ken Katakura, Daniel A. Boakye

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002630

Cytokine Network in Scrub Typhus: High Levels of Interleukin-8 Are Associated with Disease Severity and Mortality

Elisabeth Astrup, Jeshina Janardhanan, Kari Otterdal, Thor Ueland, John A. J. Prakash, Tove Lekva, Øystein A. Strand, O. C. Abraham, Kurien Thomas, Jan Kristian Damås, Prasad Mathews, Dilip Mathai, Pål Aukrust, George M. Varghese

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002648

A Structural Biology Approach to Understand Human Lymphatic Filarial Infection

Raghavendra Sashi Krishna Nagampalli, Krishnasamy Gunasekaran, Rangarajan Badri Narayanan, Angela Peters, Rajagopalan Bhaskaran

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002662

Spatial Analysis Spotlighting Early Childhood Leprosy Transmission in a Hyperendemic Municipality of the Brazilian Amazon Region

Josafá Gonçalves Barreto, Donal Bisanzio, Layana de Souza Guimarães, John Stewart Spencer, Gonzalo M. Vazquez-Prokopec, Uriel Kitron, Claudio Guedes Salgado

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002665

Anti-Anisakis IgE Seroprevalence in the Healthy Croatian Coastal Population and Associated Risk Factors

Ivona Mladineo, Vedran Poljak, Victoria Martínez-Sernández, Florencio M. Ubeira

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002673

Genome-Wide Tissue-Specific Gene Expression, Co-expression and Regulation of Co-expressed Genes in Adult Nematode Ascaris suum

Bruce A. Rosa, Douglas P. Jasmer, Makedonka Mitreva

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002678

Where Does Human Plague Still Persist in Latin America?

Maria Cristina Schneider, Patricia Najera, Sylvain Aldighieri, Deise I. Galan, Eric Bertherat, Alfonso Ruiz, Elsy Dumit, Jean Marc Gabastou, Marcos A. Espinal

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002680

Zika Virus in Gabon (Central Africa) – 2007: A New Threat from Aedes albopictus?

Gilda Grard, Mélanie Caron, Illich Manfred Mombo, Dieudonné Nkoghe, Statiana Mboui Ondo, Davy Jiolle, Didier Fontenille, Christophe Paupy, Eric Maurice Leroy

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002681

Inferring Plasmodium vivax Transmission Networks from Tempo-Spatial Surveillance Data

Benyun Shi, Jiming Liu, Xiao-Nong Zhou, Guo-Jing Yang

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002682

Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide

Mohammad Murshid Alam, Megan Kelly Bufano, Peng Xu, Anuj Kalsy, Y. Yu, Y. Wu Freeman, Tania Sultana, Md. Rasheduzzaman Rashu, Ishaan Desai, Grace Eckhoff, Daniel T. Leung, Richelle C. Charles, Regina C. LaRocque, Jason B. Harris, John D. Clements, Stephen B. Calderwood, Firdausi Qadri, W. F. Vann, Pavol Kováč, Edward T. Ryan

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002683

No Evidence for Lymphatic Filariasis Transmission in Big Cities Affected by Conflict Related Rural-Urban Migration in Sierra Leone and Liberia

Dziedzom K. de Souza, Santigie Sesay, Marnijina G. Moore, Rashid Ansumana, Charles A. Narh, Karsor Kollie, Maria P. Rebollo, Benjamin G. Koudou, Joseph B. Koroma, Fatorma K. Bolay, Daniel A. Boakye, Moses J. Bockarie

PLOS Neglected Tropical Diseases: published February 6, 2014 | https://doi.org/10.1371/journal.pntd.0002700