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August 2008

The incidence of schistosomiasis is rising globally because of irrigation and hydro-electric projects, shifts from nomadic to sedentary existence, and ineffective control programs that are not capable of coping with growing populations. To this end, the employment of automatic forecasting methods could locally support public health activities in controlling this neglected tropical disease (see Medina et al., e276).

Image Credit: Irrigation canal in Niono, Mali, by Masoud F. Tavazoie

Viewpoints

Strategies for Aspiring Biomedical Researchers in Resource-Limited Environments

Patricia J. Garcia, Walter H. Curioso

Historical Profiles and Perspectives

Yaws: A Second (and Maybe Last?) Chance for Eradication

Andrea Rinaldi

Review

Large-Scale Preventive Chemotherapy for the Control of Helminth Infection in Western Pacific Countries: Six Years Later

Antonio Montresor, Dai Tran Cong, Mouth Sinuon, Reiko Tsuyuoka, Chitsavang Chanthavisouk, Hanne Strandgaard, Raman Velayudhan, Corinne M. Capuano, Tuan Le Anh, Ah S. Tee Dató

Research Articles

Intestinal Transcriptomes of Nematodes: Comparison of the Parasites Ascaris suum and Haemonchus contortus with the Free-living Caenorhabditis elegans

Yong Yin, John Martin, Sahar Abubucker, Alan L. Scott, James P. McCarter, Richard K. Wilson, Douglas P. Jasmer, Makedonka Mitreva

The Mitochondrial Genome of Toxocara canis

Aaron R. Jex, Andrea Waeschenbach, D. Timothy J. Littlewood, Min Hu, Robin B. Gasser

Conservation and Variability of Dengue Virus Proteins: Implications for Vaccine Design

Asif M. Khan, Olivo Miotto, Eduardo J. M. Nascimento, K. N. Srinivasan, A. T. Heiny, Guang Lan Zhang, E. T. Marques, Tin Wee Tan, Vladimir Brusic, Jerome Salmon, J. Thomas August

State–Space Forecasting of Schistosoma haematobium Time-Series in Niono, Mali

Daniel C. Medina, Sally E. Findley, Seydou Doumbia

Ocular Sequelae of Congenital Toxoplasmosis in Brazil Compared with Europe

Ruth E. Gilbert, Katherine Freeman, Eleonor G. Lago, Lilian M. G. Bahia-Oliveira, Hooi Kuan Tan, Martine Wallon, Wilma Buffolano, Miles R. Stanford, Eskild Petersen, for The European Multicentre Study on Congenital Toxoplasmosis (EMSCOT)

Evaluation of Two New Commercial Tests for the Diagnosis of Acute Dengue Virus Infection Using NS1 Antigen Detection in Human Serum

Philippe Dussart, Laure Petit, Bhety Labeau, Laetitia Bremand, Alexandre Leduc, David Moua, Séverine Matheus, Laurence Baril

Entamoeba Shows Reversible Variation in Ploidy under Different Growth Conditions and between Life Cycle Phases

Chandrama Mukherjee, C. Graham Clark, Anuradha Lohia

Preventing Nerve Function Impairment in Leprosy: Validation and Updating of a Prediction Rule

Ron P. Schuring, Jan H. Richardus, Ewout W. Steyerberg, David Pahan, William R. Faber, Linda Oskam

Targets of the Entamoeba histolytica Transcription Factor URE3-BP

Carol A. Gilchrist, Duza J. Baba, Yan Zhang, Oswald Crasta, Clive Evans, Elisabet Caler, Bruno W. S. Sobral, Christina B. Bousquet, Megan Leo, Ameilia Hochreiter, Sarah K. Connell, Barbara J. Mann, William A. Petri Jr