Table of Contents

April 2008

M. corti metacestodes maintained in the peritoneal cavity of BALB/c mice were extracted, washed, and labeled with the lectins WGA–Alexa 350 (blue), Isolectin B4–Alexa 546 (red), and an anti–M. corti monoclonal antibody–Alexa 488 (green). This composite was obtained by combining images individually obtained at 400x (see Alvarez et al., e218).

Image Credit: Image generated by Jorge I. Alvarez


Stigma: The Stealth Weapon of the NTD

Peter J. Hotez

Policy Platform


Of Mice, Cattle, and Humans: The Immunology and Treatment of River Blindness

Judith E. Allen, Ohene Adjei, Odile Bain, Achim Hoerauf, Wolfgang H. Hoffmann, Benjamin L. Makepeace, Hartwig Schulz-Key, Vincent N. Tanya, Alexander J. Trees, Samuel Wanji, David W. Taylor

Research Articles

Molecular Genetics Reveal That Silvatic Rhodnius prolixus Do Colonise Rural Houses

Sinead Fitzpatrick, Maria Dora Feliciangeli, Maria J. Sanchez-Martin, Fernando A. Monteiro, Michael A. Miles

An Analysis of Genetic Diversity and Inbreeding in Wuchereria bancrofti: Implications for the Spread and Detection of Drug Resistance

Thomas S. Churcher, Anne E. Schwab, Roger K. Prichard, María-Gloria Basáñez

Early Diagnosis of Neuropathy in Leprosy—Comparing Diagnostic Tests in a Large Prospective Study (the INFIR Cohort Study)

Wim H. van Brakel, Peter G. Nicholls, Einar P. Wilder-Smith, Loretta Das, Pramila Barkataki, Diana N. J. Lockwood, on behalf of the INFIR Study Group

Human Leptospirosis Caused by a New, Antigenically Unique Leptospira Associated with a Rattus Species Reservoir in the Peruvian Amazon

Michael A. Matthias, Jessica N. Ricaldi, Manuel Cespedes, M. Monica Diaz, Renee L. Galloway, Mayuko Saito, Arnold G. Steigerwalt, Kailash P. Patra, Carlos Vidal Ore, Eduardo Gotuzzo, Robert H. Gilman, Paul N. Levett, Joseph M. Vinetz

Use of Short Tandem Repeat Sequences to Study Mycobacterium leprae in Leprosy Patients in Malawi and India

Saroj K. Young, Jorg M. Ponnighaus, Suman Jain, Sebastian Lucas, Sujai Suneetha, Diana N. J. Lockwood, Douglas B. Young, Paul E. M. Fine

Differential Gene Expression Changes in Children with Severe Dengue Virus Infections

Martijn D. de Kruif, Tatty E. Setiati, Albertus T. A. Mairuhu, Penelopie Koraka, Hella A. Aberson, C. Arnold Spek, Albert D. M. E. Osterhaus, Pieter H. Reitsma, Dees P. M. Brandjes, Augustinus Soemantri, Eric C. M. van Gorp

Tissue Invasion by Entamoeba histolytica: Evidence of Genetic Selection and/or DNA Reorganization Events in Organ Tropism

Ibne Karim M. Ali, Shahram Solaymani-Mohammadi, Jasmine Akhter, Shantanu Roy, Chiara Gorrini, Adriana Calderaro, Sarah K. Parker, Rashidul Haque, William A. Petri Jr., C. Graham Clark

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Susceptibility to Vibrio cholerae Infection in a Cohort of Household Contacts of Patients with Cholera in Bangladesh

Jason B. Harris, Regina C. LaRocque, Fahima Chowdhury, Ashraful I. Khan, Tanya Logvinenko, Abu S. G. Faruque, Edward T. Ryan, Firdausi Qadri, Stephen B. Calderwood

Interactions between Natural Populations of Human and Rodent Schistosomes in the Lake Victoria Region of Kenya: A Molecular Epidemiological Approach

Michelle L. Steinauer, Ibrahim N. Mwangi, Geoffrey M. Maina, Joseph M. Kinuthia, Martin W. Mutuku, Eric L. Agola, Ben Mungai, Gerald M. Mkoji, Eric S. Loker

Effects of Deworming on Malnourished Preschool Children in India: An Open-Labelled, Cluster-Randomized Trial

Shally Awasthi, Richard Peto, Vinod K. Pande, Robert H. Fletcher, Simon Read, Donald A. P. Bundy

A Simplified 4-Site Economical Intradermal Post-Exposure Rabies Vaccine Regimen: A Randomised Controlled Comparison with Standard Methods

Mary J. Warrell, Anna Riddell, Ly-Mee Yu, Judith Phipps, Linda Diggle, Hervé Bourhy, Jonathan J. Deeks, Anthony R. Fooks, Laurent Audry, Sharon M. Brookes, François-Xavier Meslin, Richard Moxon, Andrew J. Pollard, David A. Warrell

Immunity to Distinct Sand Fly Salivary Proteins Primes the Anti-Leishmania Immune Response towards Protection or Exacerbation of Disease

Fabiano Oliveira, Phillip G. Lawyer, Shaden Kamhawi, Jesus G. Valenzuela

Lower Expression of TLR2 and SOCS-3 Is Associated with Schistosoma haematobium Infection and with Lower Risk for Allergic Reactivity in Children Living in a Rural Area in Ghana

Franca C. Hartgers, Benedicta B. Obeng, Yvonne C. M. Kruize, Marjolijn Duijvestein, Anna de Breij, Abena Amoah, Irene A. Larbi, Ronald van Ree, Michael D. Wilson, Laura C. Rodrigues, Daniel A. Boakye, Maria Yazdanbakhsh

Impact of Environment and Social Gradient on Leptospira Infection in Urban Slums

Renato B. Reis, Guilherme S. Ribeiro, Ridalva D. M. Felzemburgh, Francisco S. Santana, Sharif Mohr, Astrid X. T. O. Melendez, Adriano Queiroz, Andréia C. Santos, Romy R. Ravines, Wagner S. Tassinari, Marília S. Carvalho, Mitermayer G. Reis, Albert I. Ko

Associations between Active Trachoma and Community Intervention with Antibiotics, Facial Cleanliness, and Environmental Improvement (A,F,E)

Jeremiah Ngondi, Fiona Matthews, Mark Reacher, Samson Baba, Carol Brayne, Paul Emerson