Table of Contents

February 2008

This scanning electron microscopy image shows a Giardia parasite attached to the carpet-like microvilli of a layer of cultured human intestinal cells. Giardia is a major cause worldwide of diarrheal illness. In this issue of PLoS Neglected Tropical Diseases, Hansen and Fletcher (e169) show that Giardia can be forced to detach from cultured intestinal cells by subjecting them to "tonic shock."

Image Credit: Wendy R. Hansen

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Tonic Shock Induces Detachment of Giardia lamblia

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