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Correction: Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma

  • Erik Koehne,
  • Nina Zander,
  • Miriam Rodi,
  • Jana Held,
  • Wolfgang Hoffmann,
  • Rella Zoleko-Manego,
  • Michael Ramharter,
  • Ghyslain Mombo-Ngoma,
  • Peter G. Kremsner,
  • Andrea Kreidenweiss
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There is an error in Table 2. The line shifted some data into the incorrect drug candidates. Please see the correct Table 2 here.

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Table 2. Drug activity against ex vivo adult worms (step 2).

https://doi.org/10.1371/journal.pntd.0010512.t001

Methylene blue, pyronaridine, and praziquantel (positive control) were exposed to the respective concentrations for 7 days (* for 24 h) followed by a 7 days drug wash-out in vitro culture.”No drug” and DMSO were the negative controls. Pooled data obtained from 3 experiments per drug are displayed.

Reference

  1. 1. Koehne E, Zander N, Rodi M, Held J, Hoffmann W, Zoleko-Manego R, et al. (2021) Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma. PLoS Negl Trop Dis 15(6): e0009511. https://doi.org/10.1371/journal.pntd.0009511 pmid:34166393