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Development and evaluation of a novel high-throughput image-based fluorescent neutralization test for detection of Zika virus infection

Fig 4

ZIKV Fluorescent neutralization test validation.

A total of 226 serum samples, among then negative and positive for flavivirus and non-flavivirus infections were examined. The neutralization titers that inhibit 90% of viral infection (NT90) are shown in the graph. Other infections: Leptospirosis, CMV, EBV, Hantavirus, Toxoplasmosis, VDRL. Dashed lines represent the test cut off: negative when NT90 <10, inconclusive when NT90 ≥10 and <20, and positive when NT90 ≥20. Symbols in blue indicate paired samples.

Fig 4