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Virulence, pathology, and pathogenesis of Pteropine orthoreovirus (PRV) in BALB/c mice: Development of an animal infection model for PRV

Fig 7

Changes in the body weight (A) and survival rate (B) in BALB/c mice challenged with a lethal dose of PRV-MB after non-lethal PRV-MB infection. BALB/c mice were pre-inoculated with a non-lethal dose (1.0 × 103 PFU) of PRV-MB or with mock solution, followed by infection with 1.0 × 105 PFU of PRV-MB on the 35th day after the first inoculation (5 mice per group). Error bars indicate the standard error.

Fig 7