Advertisement

< Back to Article

A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus

Fig 1

P1F12 mAb binds to whole ZIKV, but not DENV.

The extent of mAb binding to ZIKV and the four DENV serotypes was quantified using a virus capture ELISA. The ability of purified mAbs (1 μg / ml) to bind to captured DENV and ZIKV was assessed. Absorbance (Abs 450) values higher than three times the negative control wells were considered binders.

Fig 1

doi: https://doi.org/10.1371/journal.pntd.0005655.g001