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Predicting the Impact of Vaccination on the Transmission Dynamics of Typhoid in South Asia: A Mathematical Modeling Study

Figure 1

Model for the transmission dynamics of typhoid.

(A) Diagram of model structure. Model parameters are defined in Table 1. (B) Weekly incidence of observed (blue line) and model-predicted (thick red line) typhoid inpatients at Christian Medical College hospital in Vellore, India. The thin red line represents a simulated incidence time-series for the best-fit model assuming the number of cases each week is Poisson distributed with a mean equal to the model-predicted incidence. (C) Age distribution of observed (blue) and model-predicted (red) typhoid cases.

Figure 1