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Targeting the Wolbachia Cell Division Protein FtsZ as a New Approach for Antifilarial Therapy

Figure 7

Structures of FtsZ inhibitors and scaffolds.

General scaffolds for small molecule library compounds (A). Structure of berberine (B). FtsZ inhibitors identified from the initial high-throughput screen (C). FtsZ inhibitors identified from SAR studies (D).

Figure 7

doi: https://doi.org/10.1371/journal.pntd.0001411.g007