About the Authors

William J. Weise

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Meghan E. Hermance

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Naomi Forrester

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

A. Paige Adams

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Rose Langsjoen

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Rodion Gorchakov

Current address: Department of Pediatrics, Section of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Eryu Wang

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Maria D. H. Alcorn

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Konstantin Tsetsarkin

Current address: National Institute of Allergy and Infectious Diseases, Laboratory of Infectious Diseases, Neurotropic Flaviviruses Section, National Institutes of Health, Bethesda, Maryland, United States of America

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Scott C. Weaver

sweaver@utmb.edu

Affiliation Institute for Human Infections and Immunity, Center for Tropical Diseases, and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Competing Interests

I have read the journal's policy and have the following conflicts: SCW holds a patent for the attenuation methods used to make the vaccine described in this paper. This does not alter our adherence to all PLOS policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: WJW MEH NF APA RL RG KT SCW. Performed the experiments: WJW MEH NF APA RL RG EW MDHA KT. Analyzed the data: WJW NF APA RL SCW. Wrote the paper: WJW NF APA SCW.