About the Authors

Brian B. Gowen

brian.gowen@usu.edu

Affiliations Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, Utah, United States of America, Institute for Antiviral Research, Utah State University, Logan, Utah, United States of America, School of Veterinary Medicine, Utah State University, Logan, Utah, United States of America

Terry L. Juelich

Affiliation Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America

Eric J. Sefing

Affiliations Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, Utah, United States of America, Institute for Antiviral Research, Utah State University, Logan, Utah, United States of America

Trevor Brasel

Affiliation Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, Texas, United States of America

Jennifer K. Smith

Affiliation Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America

Lihong Zhang

Affiliation Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America

Bersabeh Tigabu

Affiliation Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, Texas, United States of America

Terence E. Hill

Affiliation Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America

Tatyana Yun

Affiliation Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America

Colette Pietzsch

Affiliation Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America

Yousuke Furuta

Affiliation Research Laboratories, Toyama Chemical Company, Ltd., Toyama, Japan

Alexander N. Freiberg

Affiliations Department of Pathology, The University of Texas Medical Branch, Galveston, Texas, United States of America, Sealy Center for Vaccine Development, The University of Texas Medical Branch, Galveston, Texas, United States of America, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, Texas, United States of America

Competing Interests

I have read the journal's policy and have the following conflicts: YF is an employee of the Toyama Chemical Co., Ltd., the manufacturer of favipiravir. This does not alter our adherence to all PLOS policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: BBG YF ANF. Performed the experiments: TLJ EJS TB JKS LZ BT TEH TY CP ANF. Analyzed the data: BBG YF ANF. Contributed reagents/materials/analysis tools: YF. Wrote the paper: BBG.