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Open Access
Peer-reviewed
Research Article
Statins Impair Antitumor Effects of Rituximab by Inducing Conformational Changes of CD20
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Magdalena Winiarska,
Affiliations Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland , Department of Laboratory Diagnostics and Clinical Immunology, the Medical University of Warsaw, Warsaw, Poland
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Jacek Bil,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Ewa Wilczek,
Affiliation Department of Pathology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Grzegorz M Wilczynski,
Affiliation Laboratory of Molecular and Systemic Neuromorphology, Nencki Institute of Experimental Biology, Warsaw, Poland
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Malgorzata Lekka,
Affiliation Department of Applied Spectroscopy, The Henryk Niewodniczanski Institute of Nuclear Physics, Krakow, Poland
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Patrick J Engelberts,
Affiliation Genmab, Utrecht, The Netherlands
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Wendy J. M Mackus,
Affiliation Genmab, Utrecht, The Netherlands
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Elzbieta Gorska,
Affiliation Department of Laboratory Diagnostics and Clinical Immunology, the Medical University of Warsaw, Warsaw, Poland
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Lukasz Bojarski,
Affiliation Laboratory of Neurodegeneration, International Institute of Molecular and Cell Biology, Warsaw, Poland
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Tomasz Stoklosa,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Dominika Nowis,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Zuzanna Kurzaj,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Marcin Makowski,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Eliza Glodkowska,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Tadeusz Issat,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Piotr Mrowka,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Witold Lasek,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Anna Dabrowska-Iwanicka,
Affiliation Department of Lymphoproliferative Disease, Maria Sklodowska-Curie Memorial Cancer Center, Institute of Oncology, Warsaw, Poland
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Grzegorz W Basak,
Affiliation Department of Hematology, Oncology and Internal Diseases, the Medical University of Warsaw, Warsaw, Poland
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Maria Wasik,
Affiliation Department of Laboratory Diagnostics and Clinical Immunology, the Medical University of Warsaw, Warsaw, Poland
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Krzysztof Warzocha,
Affiliation Institute of Hematology and Transfusion Medicine, Warsaw, Poland
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Maciej Sinski,
Affiliation Department of Internal Diseases, Hypertension and Vascular Disease, the Medical University of Warsaw, Warsaw, Poland
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Zbigniew Gaciong,
Affiliation Department of Internal Diseases, Hypertension and Vascular Disease, the Medical University of Warsaw, Warsaw, Poland
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Marek Jakobisiak,
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Paul W. H. I Parren,
Affiliation Genmab, Utrecht, The Netherlands
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Jakub Golab
*To whom correspondence should be addressed. E-mail: jgolab@ib.amwaw.edu.pl
Affiliation Department of Immunology, Center of Biostructure Research, the Medical University of Warsaw, Warsaw, Poland
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Statins Impair Antitumor Effects of Rituximab by Inducing Conformational Changes of CD20
- Magdalena Winiarska,
- Jacek Bil,
- Ewa Wilczek,
- Grzegorz M Wilczynski,
- Malgorzata Lekka,
- Patrick J Engelberts,
- Wendy J. M Mackus,
- Elzbieta Gorska,
- Lukasz Bojarski,
- Tomasz Stoklosa
- Published: March 25, 2008
- https://doi.org/10.1371/journal.pmed.0050064