Clinical and economic impact of genome-wide non-invasive prenatal testing (NIPT) as a first-tier screening method compared to targeted NIPT and first-trimester combined testing: A modeling study

• Lisanne van Prooyen Schuurman ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Writing – original draft, Writing – review & editing

  * E-mail: e.vanprooyenschuurman@erasmusmc.nl

  Affiliations Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands, Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands

  https://orcid.org/0000-0002-9971-8359

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• Harry J. de Koning,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands

  https://orcid.org/0000-0003-4682-3646

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• Eva Meier,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Ethics, Law & Humanities, Amsterdam UMC Location Vrije Universiteit, Amsterdam, the Netherlands

  https://orcid.org/0009-0008-1779-2418

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• Robert-Jan H. Galjaard,

  Roles Conceptualization, Supervision, Validation, Writing – review & editing

  Affiliation Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands

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• Nicolien T. van Ravesteyn

  Roles Conceptualization, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands

  https://orcid.org/0000-0003-3531-466X

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