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Open Access
Peer-reviewed
Research Article
Maternal dysglycaemia, changes in the infant’s epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial
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Elie Antoun ,
Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft
¶‡ EA and NTK are joint first authors. LP, KMG, and KAL are joint senior authors.
Affiliation Biological Sciences, Institute of Developmental Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, United Kingdom
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Negusse T. Kitaba ,
Roles Formal analysis, Investigation, Methodology, Writing – original draft
¶‡ EA and NTK are joint first authors. LP, KMG, and KAL are joint senior authors.
Affiliation Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯ -
Philip Titcombe,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation MRC Lifecourse Epidemiology Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
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Kathryn V. Dalrymple,
Roles Formal analysis, Investigation, Methodology, Resources, Writing – review & editing
Affiliation Department of Women and Children’s Health, School of Life Course Sciences, King’s College London, London, United Kingdom
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Emma S. Garratt,
Roles Formal analysis, Methodology, Validation, Writing – review & editing
Affiliations Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom, NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Trust, Southampton, United Kingdom
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Sheila J. Barton,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation MRC Lifecourse Epidemiology Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯ -
Robert Murray,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
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Paul T. Seed,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliation Department of Women and Children’s Health, School of Life Course Sciences, King’s College London, London, United Kingdom
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Joanna D. Holbrook,
Roles Conceptualization, Investigation, Project administration, Supervision, Writing – review & editing
Affiliation Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
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Michael S. Kobor,
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliation BC Childrens Hospital Research Institute, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, Canada
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David TS Lin,
Roles Formal analysis, Writing – review & editing
Affiliation BC Childrens Hospital Research Institute, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, Canada
⨯ -
Julia L. MacIsaac,
Roles Formal analysis, Writing – review & editing
Affiliation BC Childrens Hospital Research Institute, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, Canada
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Graham C. Burdge,
Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing
Affiliation Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯ -
Sara L. White,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Department of Women and Children’s Health, School of Life Course Sciences, King’s College London, London, United Kingdom
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Lucilla Poston ,
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft
¶‡ EA and NTK are joint first authors. LP, KMG, and KAL are joint senior authors.
Affiliation Department of Women and Children’s Health, School of Life Course Sciences, King’s College London, London, United Kingdom
⨯ -
Keith M. Godfrey ,
Roles Conceptualization, Methodology, Project administration, Resources, Supervision, Writing – original draft
¶‡ EA and NTK are joint first authors. LP, KMG, and KAL are joint senior authors.
Affiliations Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom, NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Trust, Southampton, United Kingdom
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Karen A. Lillycrop ,
Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft
* E-mail: kal@soton.ac.uk
¶‡ EA and NTK are joint first authors. LP, KMG, and KAL are joint senior authors.
Affiliations Biological Sciences, Institute of Developmental Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, United Kingdom, NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Trust, Southampton, United Kingdom
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Maternal dysglycaemia, changes in the infant’s epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial
- Elie Antoun,
- Negusse T. Kitaba,
- Philip Titcombe,
- Kathryn V. Dalrymple,
- Emma S. Garratt,
- Sheila J. Barton,
- Robert Murray,
- Paul T. Seed,
- Joanna D. Holbrook,
- Michael S. Kobor
- Published: November 5, 2020
- https://doi.org/10.1371/journal.pmed.1003229