Predicting Patterns of Long-Term CD4 Reconstitution in HIV-Infected Children Starting Antiretroviral Therapy in Sub-Saharan Africa: A Cohort-Based Modelling Study

• Marie-Quitterie Picat ,

  Contributed equally to this work with: Marie-Quitterie Picat, Joanna Lewis

  Affiliations Institute of Child Health, University College London, London, United Kingdom, Institut de Santé Publique, d'Épidémiologie et de Développement, Centre Inserm U897–Epidemiologie-Biostatistique, University of Bordeaux, Bordeaux, France, Department of Medical Information, Bordeaux University Hospital, Bordeaux, France

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• Joanna Lewis ,

  Contributed equally to this work with: Marie-Quitterie Picat, Joanna Lewis

  * E-mail: joanna.lewis@ucl.ac.uk

  Affiliations Institute of Child Health, University College London, London, United Kingdom, Centre for Mathematics and Physics in the Life Sciences and Experimental Biology, University College London, London, United Kingdom

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• Victor Musiime,

  Affiliation Joint Clinical Research Centre, Kampala, Uganda

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• Andrew Prendergast,

  Affiliations MRC Clinical Trials Unit, Medical Research Council, London, United Kingdom, Centre for Paediatrics, Blizard Institute, Queen Mary University of London, London, United Kingdom

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• Kusum Nathoo,

  Affiliation University of Zimbabwe Medical School, University of Zimbabwe, Harare, Zimbabwe

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• Addy Kekitiinwa,

  Affiliation Paediatric Infectious Diseases Centre, Mulago, Uganda

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• Patricia Nahirya Ntege,

  Affiliation MRC/UVRI Uganda Research Unit on AIDS, Uganda Virus Research Institute, Entebbe, Uganda

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• Diana M. Gibb,

  Affiliation MRC Clinical Trials Unit, Medical Research Council, London, United Kingdom

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• Rodolphe Thiebaut,

  Affiliations Institut de Santé Publique, d'Épidémiologie et de Développement, Centre Inserm U897–Epidemiologie-Biostatistique, University of Bordeaux, Bordeaux, France, Department of Medical Information, Bordeaux University Hospital, Bordeaux, France

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• A. Sarah Walker ,

  ¶These authors are joint senior authors on this work.

  Affiliation MRC Clinical Trials Unit, Medical Research Council, London, United Kingdom

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• Nigel Klein ,

  ¶These authors are joint senior authors on this work.

  Affiliation Institute of Child Health, University College London, London, United Kingdom

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• Robin Callard ,

  ¶These authors are joint senior authors on this work.

  Affiliations Institute of Child Health, University College London, London, United Kingdom, Centre for Mathematics and Physics in the Life Sciences and Experimental Biology, University College London, London, United Kingdom

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• the ARROW Trial Team

  ¶‡ Membership of the ARROW Trial Team is listed in the Acknowledgments.

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