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Open Access
Peer-reviewed
Research Article
Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis
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Timothy A Chan,
¤ Current address: Human Oncology and Pathogenesis Program and Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
Affiliations Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America , Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America
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Sabine Glockner,
Affiliations Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America , Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland, United States of America
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Joo Mi Yi,
Affiliation Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America
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Wei Chen,
Affiliations Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America , Predoctoral Training Program in Human Genetics, The Johns Hopkins University, Baltimore, Maryland, United States of America
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Leander Van Neste,
Affiliation Department of Molecular Biotechnology, Ghent University, Ghent, Belgium
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Leslie Cope,
Affiliation Biometry and Clinical Trials Division, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America
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James G Herman,
Affiliation Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America
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Victor Velculescu,
Affiliations Ludwig Center for Cancer Genetics and Therapeutics, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America , Howard Hughes Medical Institute at The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America
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Kornel E Schuebel ,
*To whom correspondence should be addressed. E-mail: sbaylin@jhmi.edu (SBB); kornels@jhmi.edu (KES); nahuja@jhmi.ed (NA)
Affiliation Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America
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Nita Ahuja ,
*To whom correspondence should be addressed. E-mail: sbaylin@jhmi.edu (SBB); kornels@jhmi.edu (KES); nahuja@jhmi.ed (NA)
Affiliations Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America , Department of Surgery, Johns Hopkins Hospital, Baltimore, Maryland, United States of America
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Stephen B Baylin
*To whom correspondence should be addressed. E-mail: sbaylin@jhmi.edu (SBB); kornels@jhmi.edu (KES); nahuja@jhmi.ed (NA)
Affiliations Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America , Predoctoral Training Program in Human Genetics, The Johns Hopkins University, Baltimore, Maryland, United States of America
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Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis
- Timothy A Chan,
- Sabine Glockner,
- Joo Mi Yi,
- Wei Chen,
- Leander Van Neste,
- Leslie Cope,
- James G Herman,
- Victor Velculescu,
- Kornel E Schuebel,
- Nita Ahuja
- Published: May 27, 2008
- https://doi.org/10.1371/journal.pmed.0050114