With disease prevention paramount in modern health care, infectious diseases relentlessly probe the capacity of health systems to protect all individuals against emerging and recognized pathogens, irrespective of countries’ wealth or stage of development. This challenge is graphically shown in the current Ebola outbreak in the Democratic Republic of the Congo, which at the time of writing has claimed an estimated 3157 cases and 2108 deaths [5]. Despite widespread alarm at the lackadaisical response to the earlier West African outbreak of 2013 to 2016, the heavy toll of mortality and ill health in the latest outbreak reminds us that research on protection of and treatment for people with emerging infectious diseases is neglected at our peril. With rising global temperatures due to climate change causing a potential domino effect, ocean expansion, spatial reorganisation of disease vectors, and displacement of communities are among the biggest health challenges of our time [6]. PLOS Medicine aims to play a crucial role in the dissemination of research in these areas as indicated by our 2017 Special Issue on Climate Change and Health [7] as well as our current Special Issue focussing on Refugee and Migrant Health [8].
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