Effects on Coronary Heart Disease of Increasing Polyunsaturated Fat in Place of Saturated Fat: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Dariush Mozaffarian; Renata Micha; Sarah Wallace

doi:10.1371/journal.pmed.1000252

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Research Article

Effects on Coronary Heart Disease of Increasing Polyunsaturated Fat in Place of Saturated Fat: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Dariush Mozaffarian ,

* E-mail: dmozaffa@hsph.harvard.edu

Affiliations Division of Cardiovascular Medicine and Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Renata Micha,

Affiliation Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯
Sarah Wallace

Affiliation Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
⨯

Effects on Coronary Heart Disease of Increasing Polyunsaturated Fat in Place of Saturated Fat: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Dariush Mozaffarian,
Renata Micha,
Sarah Wallace

Published: March 23, 2010
https://doi.org/10.1371/journal.pmed.1000252

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Impact of Additional Vegetables on Rates of CHD?

Posted by DaisyPatch on 02 May 2010 at 21:33 GMT

I am wondering if this meta-analysis took into consideration the impact of the addition of fruits, nuts, vegetables and fish to the CHD rates observed in the Oslo Diet-heart trial or to the increased fruit and vegetable intake and reduced processed food intake to the rates observed in the STARS trial?

Also I wonder, are both omega-6 rich oils and omega-3 rich oils lumped together under the heading of PUFA? If so, I would posit that they may affect the rate of CHD in uniquely different ways?

I began wondering these, and other things, after reading this blog entry: http://wholehealthsource.... (sorry about the rude title.)

No competing interests declared.

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Effects on Coronary Heart Disease of Increasing Polyunsaturated Fat in Place of Saturated Fat: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Effects on Coronary Heart Disease of Increasing Polyunsaturated Fat in Place of Saturated Fat: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

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Impact of Additional Vegetables on Rates of CHD?

Posted by DaisyPatch on 02 May 2010 at 21:33 GMT