About the Authors

Chenxi Huang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut, United States of America

Karthik Murugiah

Roles Methodology, Writing – original draft, Writing – review & editing

Affiliation Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America

Shiwani Mahajan

Roles Investigation, Writing – original draft, Writing – review & editing

Affiliation Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut, United States of America

Shu-Xia Li

Roles Formal analysis, Methodology, Validation, Writing – review & editing

Affiliation Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut, United States of America

Sanket S. Dhruva

Roles Methodology, Writing – review & editing

Affiliations Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut, United States of America

Julian S. Haimovich

Roles Methodology, Software, Writing – review & editing

Affiliation Albert Einstein College of Medicine, Bronx, New York, United States of America

Yongfei Wang

Roles Data curation, Methodology, Writing – review & editing

Affiliation Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut, United States of America

Wade L. Schulz

Roles Methodology, Writing – review & editing

Affiliations Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut, United States of America, Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America

Jeffrey M. Testani

Roles Methodology, Writing – review & editing

Affiliation Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America

Francis P. Wilson

Roles Methodology, Writing – review & editing

Affiliation Section of Nephrology, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America

Carlos I. Mena

Roles Methodology, Writing – review & editing

Affiliation Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America

Frederick A. Masoudi

Roles Investigation, Methodology, Resources, Writing – review & editing

Affiliation Division of Cardiology, School of Medicine, University of Colorado, Aurora, Colorado, United States of America

John S. Rumsfeld

Roles Investigation, Methodology, Resources, Writing – review & editing

Affiliation Division of Cardiology, School of Medicine, University of Colorado, Aurora, Colorado, United States of America

John A. Spertus

Roles Methodology, Writing – review & editing

Affiliation Department of Cardiology, Saint Luke’s Mid America Heart Institute, Kansas City, Missouri, United States of America

Bobak J. Mortazavi

Roles Conceptualization, Data curation, Methodology, Software, Writing – review & editing

‡ These authors are joint senior authors on this work.

Affiliation Department of Computer Science & Engineering, Texas A&M University, College Station, Texas, United States of America

Harlan M. Krumholz

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

harlan.krumholz@yale.edu

‡ These authors are joint senior authors on this work.

Affiliations Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut, United States of America, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America, Department of Health Policy and Management, Yale School of Public Health, New Haven, Connecticut, United States of America

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: SSD is supported by the Department of Veterans Affairs. WLS is a consultant for Hugo, a personal health information platform. CIM is a consultant for Cook, Bard, Medtronic, Abbott and Cardinal Health. FPW is supported by the National Science Foundation grant R01DK113191. JSR is the Chief Innovation Officer for the American College of Cardiology. HMK is a recipient of research agreements from Medtronic and from Johnson & Johnson (Janssen), through Yale University, to develop methods of clinical trial data sharing; was the recipient of a grant from the Food and Drug Administration and Medtronic to develop methods for postmarket surveillance of medical devices; works under contract with the Centers for Medicare and Medicaid Services to develop and maintain performance measures; chairs a cardiac scientific advisory board for UnitedHealth; is a member of the Advisory Board for Element Science and the Physician Advisory Board for Aetna; is a participant/participant representative of the IBM Watson Health Life Sciences Board; and is the founder of Hugo, a personal health information platform. JAS is supported by grants from Gilead, Genentech, Lilly, Amorcyte, and EvaHeart and has a patent for the Seattle Angina Questionnaire with royalties paid. He also owns the copyright to the Seattle Angina Questionnaire. He is the PI of an Analytic Center for the American College of Cardiology Foundation and has an equity interest in Health Outcomes Sciences. FAM has a contract (through his primary institution) for his role as Chief Science Officer of the NCDR. BJM is an associate editor for PLOS ONE, which is involved in this special issue. He has a relationship with the American College of Cardiology in selecting and pursuing innovative research based upon their registry data (unrelated to this paper). He has a pending patent application for an EHR-based prediction tool in Yale New Haven Health, as well as two funded studies, one by the DoD-Advanced Research Projects Agency and one with the NSF to support student travel to conferences in the body sensor networks field. American College of Cardiology may incorporate this work, or future iterations, into its registry. No other organisation named above has a competing interest in relation to this work. The other authors report no potential competing interests.