Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery

David A. Bennett

doi:10.1371/journal.pmed.1002256

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Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery

David A. Bennett

* E-mail: David_A_Bennett@Rush.edu

Affiliation Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America
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Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery

David A. Bennett

Published: March 14, 2017
https://doi.org/10.1371/journal.pmed.1002256

About the Authors

David A. Bennett

* E-mail: David_A_Bennett@Rush.edu

Affiliation Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America

Competing Interests

I have read the journal's policy and have the following conflicts: DAB serves on the Adjudication Committee for AD4833/TOMM40_301, Takeda Pharmaceuticals USA, Inc. and the Neuro Safety Data Monitoring Committee for ABBV-8E12, M15-566, AbbVie, Inc. DAB serves on the Scientific Advisory Board for Vigorous Minds, Inc.

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Alzheimer's disease
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Cognitive impairment
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Dementia
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Drug discovery
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Positron emission tomography
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Cerebrospinal fluid
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Clinical trials
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Clinical pathology
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