About the Authors
- Amélie Le Bihan
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Ruben de Kanter
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Iñigo Angulo-Barturen
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Affiliation GlaxoSmithKline, TresCantos Medicines Development Campus, Diseases of the Developing World, Tres Cantos, Madrid, Spain
- Christoph Binkert
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Christoph Boss
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Reto Brun
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Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
- Ralf Brunner
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Affiliations Actelion Pharmaceuticals Ltd, Allschwil, Switzerland, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
- Stephan Buchmann
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Jeremy Burrows
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Affiliation Medicines for Malaria Venture, Geneva, Switzerland
- Koen J. Dechering
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Affiliation TropIQ Health Sciences B.V., Nijmegen, The Netherlands
- Michael Delves
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Affiliation Department of Life Sciences, Imperial College London, SW7 2AZ, London, United Kingdom
- Sonja Ewerling
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Santiago Ferrer
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Affiliation GlaxoSmithKline, TresCantos Medicines Development Campus, Diseases of the Developing World, Tres Cantos, Madrid, Spain
- Christoph Fischli
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Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
- Francisco Javier Gamo–Benito
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Affiliation GlaxoSmithKline, TresCantos Medicines Development Campus, Diseases of the Developing World, Tres Cantos, Madrid, Spain
- Nina F. Gnädig
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Affiliation Department of Microbiology and Immunology, Columbia University Medical Center, New York, New York, United States of America
- Bibia Heidmann
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- María Belén Jiménez-Díaz
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Affiliation GlaxoSmithKline, TresCantos Medicines Development Campus, Diseases of the Developing World, Tres Cantos, Madrid, Spain
- Didier Leroy
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Affiliation Medicines for Malaria Venture, Geneva, Switzerland
- Maria Santos Martínez
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Affiliation GlaxoSmithKline, TresCantos Medicines Development Campus, Diseases of the Developing World, Tres Cantos, Madrid, Spain
- Solange Meyer
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Joerg J. Moehrle
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Affiliation Medicines for Malaria Venture, Geneva, Switzerland
- Caroline L. Ng
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Affiliation Department of Microbiology and Immunology, Columbia University Medical Center, New York, New York, United States of America
- Rintis Noviyanti
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Affiliation Eijkman Institute for Molecular Biology, Jakarta, Indonesia
- Andrea Ruecker
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Affiliation Department of Life Sciences, Imperial College London, SW7 2AZ, London, United Kingdom
- Laura María Sanz
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Affiliation GlaxoSmithKline, TresCantos Medicines Development Campus, Diseases of the Developing World, Tres Cantos, Madrid, Spain
- Robert W. Sauerwein
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Affiliation TropIQ Health Sciences B.V., Nijmegen, The Netherlands
- Christian Scheurer
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Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
- Sarah Schleiferboeck
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Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
- Robert Sinden
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Affiliation Department of Life Sciences, Imperial College London, SW7 2AZ, London, United Kingdom
- Christopher Snyder
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Judith Straimer
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Affiliation Department of Microbiology and Immunology, Columbia University Medical Center, New York, New York, United States of America
- Grennady Wirjanata
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Affiliation Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia
- Jutta Marfurt
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Affiliation Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia
- Ric N. Price
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Affiliations Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia, Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
- Thomas Weller
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Walter Fischli
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- David A. Fidock
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Affiliations Department of Microbiology and Immunology, Columbia University Medical Center, New York, New York, United States of America, Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center, New York, New York, United States of America
- Martine Clozel
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Affiliation Actelion Pharmaceuticals Ltd, Allschwil, Switzerland
- Sergio Wittlin
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* E-mail: sergio.wittlin@unibas.ch
Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
Competing Interests
I have read the journal's policy and the following authors of this manuscript have the following competing interests: KJD holds stocks in TropIQ Health Sciences. IAB, SF, FJGB, MBJD, MSM, LMS were employed by and owned shares of GlaxoSmithKline while conducting the studies presented. ALB, RDK, CBi, CBo, RaB, SB, SE, BH, SM, CSn,TW, WF, MC were employed by and owned shares of Actelion Pharmaceuticals Ltd while conducting the studies presented.
Author Contributions
Conceptualization: ALB RDK IAB CBi CBo ReB RaB SB JB KJD MD SE SF CF FJGB BH MBJD DL JM MSM SM JJM RN RNP AR LMS RWS CSc SS RS CSn GW TW WF MC SW NFG CLN JS DAF. Data curation: ALB RDK IAB CBi CBo ReB RaB SB JB KJD MD SE SF CF FJGB BH MBJD DL JM MSM SM JJM RN RNP AR LMS RWS CSc SS RS CSn GW TW WF MC SW NFG CLN JS DAF. Formal analysis: ALB RDK IAB CBi CBo ReB RaB SB JB KJD MD SE SF CF FJGB BH MBJD DL JMa MSM SM JJM RN RNP AR LMS RWS CSc SS RS CSn GW TW WF MC SW NFG CLN JS DAF. Funding acquisition: ALB CBi CBo ReB JB DL JJM WF DAF MC SW. Investigation: ALB RDK IAB CBi CBo ReB RaB SB JB KJD MD SE SF CF FJGB BH MBJD DL JM MSM SM JJM RN RNP AR LMS RWS CSc SS RS CSn GW TW WF MC SW NFG CLN JS DAF. Methodology: ALB RDK IAB CBi CBo ReB RaB SB JB KJD MD SE SF CF FJGB BH MBJD DL JM MSM SM JJM RN RNP AR LMS RWS CSc SS RS CSn GW TW WF MC SW NFG CLN JS DAF. Project administration: ALB. Resources: ALB RDK IAB CBi CBo ReB RaB SB JB KJD MD SE SF CF FJGB BH MBJD DL JM MSM SM JJM RN RNP AR LMS RWS CSc SS RS CSn GW TW WF MC SW NFG CLN JS DAF. Supervision: ALB RDK IAB CBi CBo ReB RaB SB JB KJD MD SE SF CF FJGB BH MBJD DL JM MSM SM JJM RN RNP AR LMS RWS CSc SS RS CSn GW TW WF MC SW NFG CLN JS DAF. Validation: ALB RDK IAB CBi CBo ReB RaB SB JB KJD MD SE SF CF FJGB BH MBJD DL JM MSM SM JJM RN RNP AR LMS RWS CSc SS RS CSn GW TW WF MC SW NFG CLN JS DAF. Visualization: ALB SW. Writing – original draft: ALB SW. Writing – review & editing: ALB RDK IAB CBi CBo ReB RaB SB JB KJD MD SE SF CF FJGB BH MBJD DL JM MSM SM JJM RN RNP AR LMS RWS CSc SS RS CSn GW TW WF MC SW NFG CLN JS DAF.