About the Authors
- Eric J Brunner
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*To whom correspondence should be addressed. E-mail: e.brunner@ucl.ac.uk
Affiliation Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, United Kingdom
- Mika Kivimäki
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Affiliation Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, United Kingdom
- Daniel R Witte
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Affiliation Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, United Kingdom
- Debbie A Lawlor
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Affiliation Medical Research Council (MRC) Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
- George Davey Smith
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Affiliation Medical Research Council (MRC) Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
- Jackie A Cooper
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Affiliation Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, Royal Free and University College London Medical School, London, United Kingdom
- Michelle Miller
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Affiliation Clinical Sciences Research Institute, Warwick Medical School, Coventry, United Kingdom
- Gordon D. O Lowe
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Affiliation Division of Cardiovascular and Medical Sciences, University of Glasgow, Royal Infirmary, Glasgow, United Kingdom
- Ann Rumley
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Affiliation Division of Cardiovascular and Medical Sciences, University of Glasgow, Royal Infirmary, Glasgow, United Kingdom
- Juan P Casas
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Affiliation Non-communicable Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
- Tina Shah
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Affiliation University College London Centre for Clinical Pharmacology, Division of Medicine, London, United Kingdom
- Steve E Humphries
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Affiliation Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, Royal Free and University College London Medical School, London, United Kingdom
- Aroon D Hingorani
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Affiliation Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, United Kingdom
- Michael G Marmot
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Affiliation Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, United Kingdom
- Nicholas J Timpson
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Affiliation Medical Research Council (MRC) Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
- Meena Kumari
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Affiliation Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, United Kingdom
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
EJB, M. Kivimäki, DAL, MM, SEH, ADH, and M. Kumari designed the study. EJB, JAC, and MM analyzed the data. MM, GDOL, AR, TS, MGM, and M. Kumari collected data or did experiments for the study. EJB and M Kivimäki wrote the first draft of the paper. EJB, M. Kivimäki, DRW, DAL, GDS, JAC, MM, GDOL, AR, JPC, ADH, MGM, NJT, and M. Kumari contributed to writing the paper. M. Kivimäki helped in conducting the data analysis and interpretation. DRW contributed to the analysis of the data. MM supervised (scientific and administrative roles) the DNA extraction program and genotyping and was responsible for checking genotype results and in particular for verifying concordance of blind duplicates, establishing error rates, etc. GDOL supervised laboratory assays. TS selected CRP tag SNPs and conducted genotyping of these SNPs. NJT helped with analysis.