About the Authors

John Danesh

Contributed equally to this work with: John Danesh, Stephen Kaptoge

To whom correspondence should be addressed. E-mail: john.danesh@phpc.cam.ac.uk

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Stephen Kaptoge

Contributed equally to this work with: John Danesh, Stephen Kaptoge

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Andrea G Mann

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Nadeem Sarwar

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Angela Wood

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Sara B Angleman

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Frances Wensley

Affiliation Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Julian P. T Higgins

Affiliation Medical Research Council Biostatistics Unit and Public Health Genetics Unit, Cambridge, United Kingdom

Lucy Lennon

Affiliation Department of Primary Care and Population Sciences, Royal Free University College London Medical School, London, United Kingdom

Gudny Eiriksdottir

Affiliations Icelandic Heart Association, Kopavogur, Iceland , University of Iceland, Kopavogur, Iceland

Ann Rumley

Affiliation Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom

Peter H Whincup

Affiliation Division of Community Health Sciences, St George's, University of London, London, United Kingdom

Gordon D. O Lowe

Affiliation Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom

Vilmundur Gudnason

Affiliations Icelandic Heart Association, Kopavogur, Iceland , University of Iceland, Kopavogur, Iceland

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JD, PHW, and VG conceived and designed the current work. SK and FW analysed the data. JD and SK drafted the paper. JD, SK, NS, AW, SBA, FW, JPTH, GE, AR, PHW, GDOL, and VG contributed to the writing of the paper. SK, AGM, NS, FW, and JPTH conducted the systematic review. LL collected the follow-up data in the BRHS. AR and GDOL supervised IL-6 assays.