About the Authors
- Philip Bejon
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*To whom correspondence should be addressed. E-mail: pbejon@kilifi.kemri-wellcome.org
Affiliations Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya , Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, United Kingdom
- James A Berkley
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Affiliations Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya , Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, United Kingdom
- Tabitha Mwangi
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Affiliation Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya
- Edna Ogada
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Affiliation Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya
- Isaiah Mwangi
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Affiliation Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya
- Kathryn Maitland
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Affiliations Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya , Department of Paediatrics, Imperial College, London, United Kingdom , Wellcome Trust Centre for Clinical Tropical Medicine, Imperial College, London, United Kingdom
- Thomas Williams
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Affiliations Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya , Department of Paediatrics, The John Radcliffe Hospital University of Oxford, Oxford, United Kingdom
- J. Anthony G Scott
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Affiliations Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya , Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, United Kingdom
- Mike English
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Affiliations Department of Paediatrics, The John Radcliffe Hospital University of Oxford, Oxford, United Kingdom , Nairobi KEMRI–Wellcome Trust Collaborative Research Programme, Kenyatta National Hospital, Nairobi, Kenya
- Brett S Lowe
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Affiliations Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya , Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, United Kingdom
- Norbert Peshu
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Affiliation Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya
- Charles R. J. C Newton
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Affiliations Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya , Neurosciences Unit, Institute of Child Health, London, United Kingdom
- Kevin Marsh
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Affiliations Kenya Medical Research Institute (KEMRI)–Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research (Coast), Kilifi, Kenya , Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, United Kingdom
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
The manuscript was written by P. Bejon, J. Berkley, C. Newton, and K. Marsh. Laboratory studies were conducted by B. Lowe. Clinical support was given by T. Mwangi, I. Mwangi, K. Maitland, J. Scott, M. English, N. Peshu, and C. Newton. Inpatient data were collected by K. Maitland, J. Scott, M. English, C. Newton, and K. Marsh. Outpatient data were collected by T. Mwangi, E. Ogada, and T. Williams. P. Bejon analysed the data. K. Maitland, J. Scott, and C. Newton contributed to interpretation of the results. All authors approved the final manuscript. P. Bejon had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.