Optimizing the Dose of Pre-Pandemic Influenza Vaccines to Reduce the Infection Attack Rate

Steven Riley; Joseph T Wu; Gabriel M Leung

doi:10.1371/journal.pmed.0040218

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Open Access

Peer-reviewed

Research Article

Optimizing the Dose of Pre-Pandemic Influenza Vaccines to Reduce the Infection Attack Rate

Steven Riley ,

Contributed equally to this work with: Steven Riley, Joseph T Wu

*To whom correspondence should be addressed. E-mail: steven.riley@hku.hk

Affiliation Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China
⨯
Joseph T Wu ,

Contributed equally to this work with: Steven Riley, Joseph T Wu

Affiliation Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China
⨯
Gabriel M Leung

Affiliation Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China
⨯

Optimizing the Dose of Pre-Pandemic Influenza Vaccines to Reduce the Infection Attack Rate

Steven Riley,
Joseph T Wu,
Gabriel M Leung

Published: June 19, 2007
https://doi.org/10.1371/journal.pmed.0040218

About the Authors

Steven Riley

Contributed equally to this work with: Steven Riley, Joseph T Wu

*To whom correspondence should be addressed. E-mail: steven.riley@hku.hk

Affiliation Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China

Joseph T Wu

Contributed equally to this work with: Steven Riley, Joseph T Wu

Affiliation Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China

Gabriel M Leung

Affiliation Department of Community Medicine and School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

All authors contributed to study design, interpretation of findings, and writing the paper. SR and JTW analysed the data. SR wrote the first draft of the manuscript and constructed an independent model to validate key findings. JTW designed and implemented the main mathematical model and identified previously published data sets in the literature.

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Vaccines
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Vaccine development
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Stockpiles
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Influenza
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Vaccination and immunization
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Pandemics
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Viral vaccines
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Medical risk factors
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