About the Authors

Xiao-Bing Zhang

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Brian C Beard

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Katherine Beebe

Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Barry Storer

Affiliations Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America , Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

R. Keith Humphries

Affiliations Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada , Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

Hans-Peter Kiem

To whom correspondence should be addressed. E-mail: hkiem@fhcrc.org

Affiliations Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America , Departments of Medicine and Pathology, University of Washington, Seattle, Washington, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

XBZ performed the experiments. BCB performed the integration-site studies. KB assisted with the analysis of the experiments. BS performed the statistical analyses. RKH assisted with the design and interpretation of results. HPK designed the experiments and wrote the paper.